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Gary B. Braun

Researcher at Discovery Institute

Publications -  75
Citations -  5532

Gary B. Braun is an academic researcher from Discovery Institute. The author has contributed to research in topics: Nanoparticle & Silver nanoparticle. The author has an hindex of 39, co-authored 74 publications receiving 4965 citations. Previous affiliations of Gary B. Braun include University of Illinois at Urbana–Champaign & Stemcell Technologies.

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Fabrication of Ag@SiO2@Y2O3:Er Nanostructures for Bioimaging: Tuning of the Upconversion Fluorescence with Silver Nanoparticles

TL;DR: It is demonstrated that the nanostructures comprising silver cores and dense layers of Y(2)O(3):Er separated by a silica shell are an excellent model system to study the interaction between upconversion materials and metals in nanoscale.
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Mesoporous Multifunctional Upconversion Luminescent and Magnetic “Nanorattle” Materials for Targeted Chemotherapy

TL;DR: In vivo experiments yield highly encouraging tumor shrinkage with the antitumor drug doxorubicin (DOX) and significantly enhanced tumor targeting in the presence of an applied magnetic field.
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Surface-enhanced Raman spectroscopy for DNA detection by nanoparticle assembly onto smooth metal films.

TL;DR: AFM analysis indicates that strong SERS signal intensity arises from only a few surface-bound nanoparticles which generate an enhancement factor ∼105−106 greater than the metal film alone.
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Laser-Activated Gene Silencing via Gold Nanoshell−siRNA Conjugates

TL;DR: The pulsed near-infrared (NIR) laser-dependent release of siRNA from coated 40 nm gold nanoshells is demonstrated, which should facilitate more sophisticated developmental biology and therapeutic studies.
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Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy.

TL;DR: It is shown that conjugation of vancomycin-loaded nanoparticles with the cyclic 9-amino-acid peptide CARGGLKSC (CARG), identified via phage display on Staphylococcus aureus, increases the antibacterial activity of the nanoparticles in S. a Aureus-infected tissues and reduces the systemic dose needed, minimizing side effects.