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Gary J. Patti

Researcher at Washington University in St. Louis

Publications -  139
Citations -  11749

Gary J. Patti is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Metabolomics & Medicine. The author has an hindex of 44, co-authored 111 publications receiving 8976 citations. Previous affiliations of Gary J. Patti include Barnes-Jewish Hospital & Scripps Research Institute.

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Journal ArticleDOI

Innovation: Metabolomics: the apogee of the omics trilogy

Gary J. Patti, +2 more
- 22 Mar 2012 - 
TL;DR: By performing global metabolite profiling, also known as untargeted metabolomics, new discoveries linking cellular pathways to biological mechanism are being revealed and are shaping the understanding of cell biology, physiology and medicine.
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XCMS Online: A Web-Based Platform to Process Untargeted Metabolomic Data

Ralf Tautenhahn, +3 more
- 10 May 2012 - 
TL;DR: XCMS Online provides a solution for the complete untargeted metabolomic workflow including feature detection, retention time correction, alignment, annotation, statistical analysis, and data visualization.
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Metabolic oxidation regulates embryonic stem cell differentiation

Oscar Yanes, +9 more
- 01 Jun 2010 - 
TL;DR: It is demonstrated that the stem cell redox status is regulated during differentiation and postulate that the highly unsaturated metabolome sustained by stem cells makes them particularly attuned to differentiate in response to in vivo oxidative processes such as inflammation.
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An accelerated workflow for untargeted metabolomics using the METLIN database.

Ralf Tautenhahn, +5 more
- 10 Sep 2012 - 
TL;DR: Although relatively new compared to its genomic and proteomic predecessors, metabolomics has led to the discovery of biomarkers for disease, fundamental insights into cellular biochemistry, and clues related to disease pathogenesis.
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Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State.

Leslie Magtanong, +11 more
- 21 Mar 2019 - 
TL;DR: It is found that exogenous monounsaturated fatty acids (MUFAs) potently inhibit the non-apoptotic, iron-dependent, oxidative cell death process of ferroptosis and protects cells from apoptotic lipotoxicity caused by the accumulation of saturated fatty acids, but in an ACSL3-independent manner.