G
Gary J. Vora
Researcher at United States Naval Research Laboratory
Publications - 76
Citations - 2825
Gary J. Vora is an academic researcher from United States Naval Research Laboratory. The author has contributed to research in topics: Vibrio campbellii & Drug resistance. The author has an hindex of 27, co-authored 74 publications receiving 2417 citations. Previous affiliations of Gary J. Vora include University of Massachusetts Amherst & Scripps Research Institute.
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Journal ArticleDOI
Broad-spectrum respiratory tract pathogen identification using resequencing DNA microarrays
Baochuan Lin,Zheng Wang,Gary J. Vora,Jennifer Thornton,Joel M. Schnur,Dzung C. Thach,Kate M. Blaney,Adam G. Ligler,Anthony P. Malanoski,Jose Santiago,Elizabeth A. Walter,Brian K. Agan,David Metzgar,Donald Seto,Luke T. Daum,Russell P. Kruzelock,Robb K. Rowley,Eric H. Hanson,Clark Tibbetts,David A. Stenger +19 more
TL;DR: Successful proof-of-concept experiments demonstrate the ability of this approach for correct species- and strain-level identification with unambiguous statistical interpretation at clinically relevant sensitivity levels, and underscore the feasibility of using this approach to expedite the early surveillance of diseases, and provide new information on the incidence of multiple pathogens.
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Comparative genomic analyses identify the Vibrio harveyi genome sequenced strains BAA-1116 and HY01 as Vibrio campbellii
Baochuan Lin,Zheng Wang,Anthony P. Malanoski,Elizabeth A. O'Grady,Charles F. Wimpee,Varaporn Vuddhakul,Nelson A. Alves,Fabiano L. Thompson,Bruno Gomez-Gil,Gary J. Vora +9 more
TL;DR: These findings correct a number of species misidentifications while validating the ability of both CGH and MLSA to distinguish closely related members of the Harveyi clade.
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Nucleic acid amplification strategies for DNA microarray-based pathogen detection.
TL;DR: The results presented here underscore the feasibility of using random amplification approaches and begin to systematically address the versatility of these approaches for unbiased pathogen detection from environmental sources.
Journal ArticleDOI
Microarray-based detection of genetic heterogeneity, antimicrobial resistance, and the viable but nonculturable state in human pathogenic Vibrio spp.
Gary J. Vora,Carolyn E. Meador,Michele M. Bird,Cheryl A. Bopp,Joanne D. Andreadis,David A. Stenger +5 more
TL;DR: A single multiplex PCR assay to simultaneously amplify 95 diagnostic regions and combined it with a long oligonucleotide microarray to create a platform capable of rapidly detecting and discriminating the major human pathogenic species from the genus Vibrio is designed.
Journal ArticleDOI
Fluorescent signal amplification of carbocyanine dyes using engineered viral nanoparticles.
Carissa M. Soto,Amy Szuchmacher Blum,Gary J. Vora,Nikolai Lebedev,Carolyn E. Meador,Angela P. Won,Anju Chatterji,John E. Johnson,Banahalli R. Ratna +8 more
TL;DR: These viral nanoparticles markedly increased assay sensitivity in a microarray-based genotyping assay for Vibrio cholerae O139, thus demonstrating their applicability for existing DNA microarray protocols.