G
Gavin Hamilton
Researcher at University of California, San Diego
Publications - 129
Citations - 9638
Gavin Hamilton is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Fatty liver & Nonalcoholic fatty liver disease. The author has an hindex of 46, co-authored 127 publications receiving 8415 citations. Previous affiliations of Gavin Hamilton include Hammersmith Hospital & Ottawa Hospital Research Institute.
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Journal ArticleDOI
Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy
TL;DR: Magnetic resonance (MR) techniques can decompose the liver signal into its fat and water signal components and therefore assess liver fat more directly than CT or US and are likely to be commercially available soon.
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In vivo characterization of the liver fat 1H MR spectrum
Gavin Hamilton,Takeshi Yokoo,Mark Bydder,Irene Cruite,Michael E. Schroeder,Claude B. Sirlin,Michael S. Middleton +6 more
TL;DR: The triglyceride model can characterize human liver fat spectra, which allows more accurate determination of liver fat fraction from MRI and MRS, and agreed closely with spectroscopic measurement.
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Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials
Mazen Noureddin,Jessica Lam,Michael R. Peterson,Michael S. Middleton,Gavin Hamilton,Thuy-Anh Le,Ricki Bettencourt,Christopher Changchien,David A. Brenner,Claude B. Sirlin,Rohit Loomba +10 more
TL;DR: MRI‐ PDFF correlated well with MRS‐PDFF and was more sensitive than the histology‐determined steatosis grade in quantifying increases or decreases in the liver fat content, and could be used to quantify changes in liver fat in future clinical trials.
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Nonalcoholic Fatty Liver Disease: MR Imaging of Liver Proton Density Fat Fraction to Assess Hepatic Steatosis
An Tang,Justin Tan,Mark Sun,Gavin Hamilton,Mark Bydder,Tanya Wolfson,Anthony Gamst,Michael S. Middleton,Elizabeth M. Brunt,Rohit Loomba,Joel E. Lavine,Jeffrey B. Schwimmer,Claude B. Sirlin +12 more
TL;DR: MR imaging-PDFF showed promise for assessment of hepatic steatosis grade in patients with NAFLD, and was significantly correlated with histologic steatotic grade.
Journal ArticleDOI
Relaxation Effects in the Quantification of Fat using Gradient Echo Imaging
Mark Bydder,Takeshi Yokoo,Gavin Hamilton,Michael S. Middleton,Alyssa D. Chavez,Jeffrey B. Schwimmer,Joel E. Lavine,Claude B. Sirlin +7 more
TL;DR: Quantification of fat has been investigated using images acquired from multiple gradient echoes and results indicate that quantification is most accurate at low flip angles with a small number of echoes (to minimize spectral broadening effects).