Geng Zhang

TL;DR: Phytochemical investigation of the whole plant of Ainsliaea fragrans afforded five new coumarin derivatives, including a pair of natural 4-hydroxycoumarin enantiomers with a rare polycyclic pyrano[3-2c] carbon skeleton, together with 5 known biogenetically related compounds.

TL;DR: The findings suggested that indole diketopiperazines from endophytic Chaetomium sp 88194 may be potential resource for developing anti-cancer reagents.

TL;DR: A rare depsipeptide, chaetomiamide A, together with two known diketopiperazines (2, 3) were isolated from the cultures of endophytic fungus Chaetomium sp.

TL;DR: Fuzi, ganjiang and fuzi-ganjiang combination possess prominent anti-inflammatory activities against DSS-induced UC mice; the involved mechanism may be related to inhibition the activation of MAPK, NF-κB, and STAT3 signaling pathways.

TL;DR: Three new clerodane type diterpenoids (2-4), together with one known analogues (1), were isolated from the tuberous roots of Tinospora sagittata (Oliv.) Gagnep and evaluated for their cytotoxic activities against five human cancer cell lines and inhibitory activities on LPS-induced NO production in RAW264.7 cells.