Geoffrey L. Chupp

TL;DR: The RealITI-A was a 24-month international, prospective, observational cohort study involving 84 centers across Europe, Canada, and the United States, with a 1-year pre-post mepolizumab treatment preplanned interim analysis as discussed by the authors .

TL;DR: It is concluded that the complex relationship between these two disease processes warrants further investigation.

TL;DR: A pipeline that integrates dimensionality reduction and statistical modeling to grapple with the heterogeneity of sputum samples is developed and LDA(Latent Dirichlet allocation)-link connects microbes to genes using reduced-dimensionality LDA topics.

TL;DR: In this article , the authors used data from the REDES study to assess the proportion of patients with severe eosinophilic asthma achieving their multicomponent definitions of clinical remission after 1 year of mepolizumab treatment.

TL;DR: In this article , dupilumab was shown to reduce severe asthma exacerbation rates and changes from parent study baseline (PSBL) in pre-bronchodilator FEV1 and 5-item asthma control questionnaire (ACQ-5) score in patients with moderate-to-severe type 2 asthma with and without evidence of allergic asthma at PSBL.