Preface. Acknowledgements. Introduction. References. List of Structures. Index of Abbreviations. Diagrams.

The Rat Brain in Stereotaxic Coordinates

Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

Staging of brain pathology related to sporadic Parkinson’s disease

Thirty years of brain imaging research has converged to define the brain’s default network—a novel and only recently appreciated brain system that participates in internal modes of cognition Here we synthesize past observations to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment Analysis of connectional anatomy in the monkey supports the presence of an interconnected brain system Providing insight into function, the default network is active when individuals are engaged in internally focused tasks including autobiographical memory retrieval, envisioning the future, and conceiving the perspectives of others Probing the functional anatomy of the network in detail reveals that it is best understood as multiple interacting subsystems The medial temporal lobe subsystem provides information from prior experiences in the form of memories and associations that are the building blocks of mental simulation The medial prefrontal subsystem facilitates the flexible use of this information during the construction of self-relevant mental simulations These two subsystems converge on important nodes of integration including the posterior cingulate cortex The implications of these functional and anatomical observations are discussed in relation to possible adaptive roles of the default network for using past experiences to plan for the future, navigate social interactions, and maximize the utility of moments when we are not otherwise engaged by the external world We conclude by discussing the relevance of the default network for understanding mental disorders including autism, schizophrenia, and Alzheimer’s disease

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The Brain's Default Network Anatomy, Function, and Relevance to Disease

I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

Principles of Neural Science

A segmentation guide and probabilistic atlas of the C57BL/6J mouse brain from magnetic resonance imaging

Publisher Summary This chapter discusses angiotensin-converting enzyme (ACE) in human brain, which converts angiotensin I (Ang I) to angiotensinII (Ang II), a peptide important in the central regulation of blood pressure and fluid and electrolyte homeostasis. Moderate binding is found in the substantia innominata and high intensity of labeling is also present in fibers that exit from the medial part of the internal globus pallidus. The gelatinosus subnucleus of the spinal trigeminal nucleus displays moderate binding as do all the subdivisions of the inferior olivary nucleus. The circumventricular organs have deficient blood–brain barriers and therefore, ACE is responsible for either the conversion of blood-borne Ang I or the production of endogenous neuronal Ang II to influence central mechanisms involved in fluid and electrolyte balance and blood pressure control. Receptors for Ang II are in high concentrations in the human paraventricular nucleus. The overall pattern of ACE distribution in the human brain has high concentrations of enzyme found in the basal ganglia.

George Paxinos

Papers

A segmentation guide and probabilistic atlas of the C57BL/6J mouse brain from magnetic resonance imaging

Angiotensin-Converting Enzyme in the Human Brain

Erratum: Revised nomenclature for avian telencephalon and some related brainstem nuclei (Journal of Comparative Neurology (2004) 473 (377-414))

The brain's anatomy

RETRACTED: Preface: Second Edition