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George T.-J. Huang

Researcher at University of Tennessee Health Science Center

Publications -  106
Citations -  10395

George T.-J. Huang is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Pulp (tooth) & Dental pulp stem cells. The author has an hindex of 41, co-authored 102 publications receiving 9159 citations. Previous affiliations of George T.-J. Huang include University of Maryland University College & University of Maryland, College Park.

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Mesenchymal Stem Cells Derived from Dental Tissues vs. Those from Other Sources: Their Biology and Role in Regenerative Medicine

TL;DR: This article will review the isolation and characterization of the properties of different dental MSC-like populations in comparison with those of other MSCs, such as BMMSCs.
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Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth: A Pilot Study

TL;DR: The apical papilla is distinctive to the pulp in terms of containing less cellular and vascular components than those in the pulp, and both SCAP and DPSCs were as potent in osteo/dentinogenic differentiation as MSCs from bone marrows, whereas they were weaker in adipogenic potential.
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The hidden treasure in apical papilla: the potential role in pulp/dentin regeneration and bioroot engineering.

TL;DR: The potential role of mesenchymal stem cells in the following respects will be discussed: their contribution in continued root maturation in endodontically treated immature teeth with periradicular periodontitis or abscess and their potential utilization for pulp/dentin regeneration and bioroot engineering.
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Stem/Progenitor Cell–Mediated De Novo Regeneration of Dental Pulp with Newly Deposited Continuous Layer of Dentin in an In Vivo Model

TL;DR: This study provides the first evidence showing that pulp- like tissue can be regenerated de novo in emptied root canal space by stem cells from apical papilla and dental pulp stem cells that give rise to odontoblast-like cells producing dentin-like tissue on existing dentinal walls.
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Histologic characterization of regenerated tissues in canal space after the revitalization/revascularization procedure of immature dog teeth with apical periodontitis.

TL;DR: These findings explained in part why many clinical cases of immature teeth with apical periodontitis or abscess may gain root thickness and apical length after conservative treatment with the revitalization procedure.