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Wataru Sonoyama
Researcher at Okayama University
Publications - 56
Citations - 7851
Wataru Sonoyama is an academic researcher from Okayama University. The author has contributed to research in topics: Stem cell & Mesenchymal stem cell. The author has an hindex of 29, co-authored 56 publications receiving 7125 citations. Previous affiliations of Wataru Sonoyama include University of Southern California & National Institutes of Health.
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Journal ArticleDOI
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche
Yanming Bi,Driss Ehirchiou,Tina M. Kilts,Colette A. Inkson,Mildred C. Embree,Wataru Sonoyama,Li Li,Arabella I. Leet,Byoung Moo Seo,Li Zhang,Songtao Shi,Songtao Shi,Marian F. Young +12 more
TL;DR: It is shown that human and mouse tendons harbor a unique cell population, termed tendon stem/progenitor cells (TSPCs), that has universal stem cell characteristics such as clonogenicity, multipotency and self-renewal capacity and could regenerate tendon-like tissues after extended expansion in vitro and transplantation in vivo.
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Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine
Wataru Sonoyama,Wataru Sonoyama,Yi Liu,Dianji Fang,Takayoshi Yamaza,Byoung Moo Seo,Chunmei Zhang,He Liu,Stan Gronthos,Cun-Yu Wang,Songtao Shi,Songlin Wang +11 more
TL;DR: This work transplanted both human SCAP and periodontal ligament stem cells to generate a root/periodontal complex capable of supporting a porcelain crown, resulting in normal tooth function and recovery of tooth strength and appearance.
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Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth: A Pilot Study
Wataru Sonoyama,Yi Liu,Takayoshi Yamaza,Rocky S. Tuan,Songlin Wang,Songtao Shi,George T.-J. Huang +6 more
TL;DR: The apical papilla is distinctive to the pulp in terms of containing less cellular and vascular components than those in the pulp, and both SCAP and DPSCs were as potent in osteo/dentinogenic differentiation as MSCs from bone marrows, whereas they were weaker in adipogenic potential.
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The hidden treasure in apical papilla: the potential role in pulp/dentin regeneration and bioroot engineering.
TL;DR: The potential role of mesenchymal stem cells in the following respects will be discussed: their contribution in continued root maturation in endodontically treated immature teeth with periradicular periodontitis or abscess and their potential utilization for pulp/dentin regeneration and bioroot engineering.
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Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation
Masako Miura,Yasuo Miura,Hesed Padilla-Nash,Alfredo A. Molinolo,Baojin Fu,Vyomesh Patel,Byoung Moo Seo,Wataru Sonoyama,Jenny J. Zheng,Carl C. Baker,Wanjun Chen,Thomas Ried,Songtao Shi +12 more
TL;DR: It is demonstrated that murine BMMSCs, after numerous passages, obtained unlimited population doublings and proceeded to a malignant transformation state, resulting in fibrosarcoma formation in vivo, which may provide an ideal system to elucidate the mechanism of how stem cells become cancer cells and to screen anti‐sarcomA drugs.