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Geraldine S. Pinkus
Researcher at Brigham and Women's Hospital
Publications - 286
Citations - 29136
Geraldine S. Pinkus is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Lymphoma & Immunoperoxidase. The author has an hindex of 84, co-authored 278 publications receiving 27112 citations. Previous affiliations of Geraldine S. Pinkus include University of Texas MD Anderson Cancer Center & Montreal General Hospital.
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Journal Article
Intracellular myoglobin--a specific marker for skeletal muscle differentiation in soft tissue sarcomas. An immunoperoxidase study
TL;DR: The immunoperoxidase method affords a sensitive and specific method for identifying rhabdomyoblasts in tissue on the basis of intracellular myoglobin and is of use in distinguishing rhabDomyosarcomas from other sarcomas and from malignant tumors of other types.
Journal ArticleDOI
Immunosurveillance and Survivin-Specific T-Cell Immunity in Children With High-Risk Neuroblastoma
Christina M. Coughlin,Mark D. Fleming,Richard G. Carroll,Bruce R. Pawel,Michael D. Hogarty,Xiaochuan Shan,Barbara A. Vance,Jarish N. Cohen,Sonya Jairaj,Elaina M. Lord,Michael H. Wexler,Gwenn-ael Danet-Desnoyers,Jack L. Pinkus,Geraldine S. Pinkus,John M. Maris,Stephan A. Grupp,Robert H. Vonderheide +16 more
TL;DR: Children with HR-NBL harbor robust cellular immune responses to the universal tumor antigen survivin at the time of diagnosis, but intratumoral T cells are strikingly rare, suggesting a failure of cellular immunosurveillance.
Journal ArticleDOI
First reported cases of intravascular large cell lymphoma of the NK cell type: clinical, histologic, immunophenotypic, and molecular features.
Huiqing Wu,J. W. Said,Elizabeth D. Ames,Chen Chen,Valerie McWhorter,Peter P. Chen,Violette Ghali,Geraldine S. Pinkus +7 more
TL;DR: This report is the first to describe the clinical, histologic, immunophenotypic, and molecular features of 2 cases of intravascular lymphoma with an NK cell phenotype (CD3epsilon+, CD2+, CD7+, CD56+, T-cell intracytoplasmic antigen-1+, perforin+, granzyme B+, CD20-, CD4-, CD5-, CD8-, T- cell receptor [TCR]betaF1-).
Journal Article
Immunohistochemical localization of smooth muscle myosin in human spleen, lymph node, and other lymphoid tissues. Unique staining patterns in splenic white pulp and sinuses, lymphoid follicles, and certain vasculature, with ultrastructural correlations
TL;DR: Certain vascular structures, specifically sinus lining cells and Schweigger-Seidel capillary sheaths of the spleen and postcapillary venules of lymph nodes and tonsils, coexpressed smooth muscle myosin and Factor VIII associated antigen.
Journal Article
Distinction between small lymphocytic and mantle cell lymphoma by immunoreactivity for CD23.
TL;DR: Immunoreactivity for CD23 appears to be a useful marker to aid in distinguishing SLL/CLL from MCL and may be helpful in routine immunophenotypic screening of low-grade B-cell derived lymphoproliferative processes.