G
Gerard C. L. Wong
Researcher at University of California, Los Angeles
Publications - 183
Citations - 10694
Gerard C. L. Wong is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Antimicrobial peptides & Membrane. The author has an hindex of 51, co-authored 173 publications receiving 8831 citations. Previous affiliations of Gerard C. L. Wong include California Institute of Technology & University of California, Berkeley.
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Journal ArticleDOI
Silver nanoparticles boost charge-extraction efficiency in Shewanella microbial fuel cells.
Bocheng Cao,Zipeng Zhao,Lele Peng,Hui-Ying Shiu,Mengning Ding,Frank Song,Xun Guan,Calvin K. Lee,Jin Huang,Dan Zhu,Xiaoyang Fu,Gerard C. L. Wong,Chong Liu,Kenneth H. Nealson,Paul S. Weiss,Xiangfeng Duan,Yu Huang +16 more
TL;DR: In this paper, the authors proposed a method to directly convert the chemical energy stored in organic matter to electricity and are of considerable interest for power generation and wastewater treatment using microbial fuel cells (MFCs).
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Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids
Lihua Yang,Vernita Gordon,Dallas R. Trinkle,Nathan W. Schmidt,Matthew A. Davis,Clarabelle DeVries,Abhigyan Som,John E. Cronan,Gregory N. Tew,Gerard C. L. Wong +9 more
TL;DR: It is shown unambiguously that bacterial membrane permeation by these antimicrobials depends on the presence of negative intrinsic curvature lipids, such as phosphatidylethanolamine (PE)lipids, found in high concentrations within bacterial membranes.
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C-di-GMP Regulates Motile to Sessile Transition by Modulating MshA Pili Biogenesis and Near-Surface Motility Behavior in Vibrio cholerae.
Christopher J. Jones,Andrew S. Utada,Kimberly R. Davis,Wiriya Thongsomboon,David Zamorano Sanchez,Vinita Banakar,Lynette Cegelski,Gerard C. L. Wong,Fitnat H. Yildiz +8 more
TL;DR: The results suggest that the dynamic nature of the MshA pilus established by the assembly and disassembly of pilin subunits is essential for transition from the motile to sessile lifestyle and that c-di-GMP affects Msh a pilus assembly and function through direct interactions with the MShE ATPase.
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Lamellar phase of stacked two-dimensional rafts of actin filaments.
TL;DR: It is shown that as a function of increasing ion concentration, the F-actin rods in either an isotropic or a nematic phase will transform into a new and unexpected lamellar phase of cross-linked rafts (L(XR) phase), before condensing into a bundled phase of parallel, close-packed rods.
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Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission.
TL;DR: These studies establish the importance of M2-induced NGC during budding and suggest that antagonizing this curvature is a viable anti-influenza strategy.