Gerco C. Angenent

TL;DR: This study provides a solid base for functional genomics studies into this important family of plant regulatory genes, including the poorly characterized group of M-type MADS-box proteins.

TL;DR: A comprehensive plant protein–protein interactome map of nearly all members of the Arabidopsis thaliana MADS box transcription factor family is presented and a model is proposed that integrates the floral induction and floral organ formation networks based on the interactions between the proteins involved.

TL;DR: Analysis of the molecular mechanisms underlying AP1 function indicates that it functions first to repress vegetative identity, then to help establish floral primordia, and finally to shape the differentiation of floral parts, implying that AP1 orchestrates floral initiation by integrating growth, patterning, and hormonal pathways.

TL;DR: Recent findings on MADS-box gene functions in Arabidopsis are reviewed and the evolutionary history and functional diversification of this gene family in plants are discussed.

TL;DR: A targeted proteomics approach was able to establish a MADS-domain protein interactome that strongly supports a mechanistic link between MADs-domain proteins and chromatin remodeling factors and members of other transcription factor families were identified as interaction partners suggesting various specific combinatorial modes of action.