Gertrud Mannhaupt

TL;DR: The role of Rpn4p to function as a transregulator in yeast is corroborated by its ability of stimulating proteasome‐associated control element‐driven lacZ expression and by experiments using the RPT4 and RPT6 gene promoters coupled to the bacterial cat gene as a reporter.

TL;DR: Two AAA proteases with their catalytic sites on opposite membrane surfaces constitute a novel proteolytic system for the degradation of membrane proteins in mitochondria.

TL;DR: Surprisingly, for seven genes, additional, unexpected phenotypes were found in the authors' tests, suggesting that the type of analysis presented here provides a more complete description of gene function.

TL;DR: This work has identified 12 different members of this novel gene family (the YTA family) in yeast and determined the nucleotide sequences of nine of these genes, and proposed that YTA1, Yta2, YTA3 and YTA5 function as regulatory subunits of the yeast 26S proteasome.

TL;DR: Comparison of the known DNA sequence with the partial protein sequence obtained reveals that six of the 15 residues are hydrophilic and, unlike most signal sequences, this transient sequence does not contain extended hydrophobic parts.