Irene Vetter

TL;DR: The role of Rpn4p to function as a transregulator in yeast is corroborated by its ability of stimulating proteasome‐associated control element‐driven lacZ expression and by experiments using the RPT4 and RPT6 gene promoters coupled to the bacterial cat gene as a reporter.

TL;DR: This work has identified 12 different members of this novel gene family (the YTA family) in yeast and determined the nucleotide sequences of nine of these genes, and proposed that YTA1, Yta2, YTA3 and YTA5 function as regulatory subunits of the yeast 26S proteasome.

TL;DR: The cloning of TKL2, a gene coding for a second transketolase enzyme in Saccharomyces cerevisiae, is described and it is shown that TKWL2 is functionally expressed and the protein reacts with anti-transketol enzyme serum in Western blot analysis.

TL;DR: It is shown that HMR and LHR form a centromeric complex necessary for proper chromosome segregation, and this work provides evidence for a major role of centromere divergence in the generation of biodiversity.

TL;DR: A comprehensive analysis of the proteomic composition of Drosophila centromeres is provided and RNA interference mediated depletion of CG2051, CG14480, and hyperplastic discs, three of the strongest candidates, leads to elevated mitotic defects.