G
Ghislain Fournous
Researcher at Aix-Marseille University
Publications - 26
Citations - 4381
Ghislain Fournous is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Giant Virus & Mimivirus. The author has an hindex of 23, co-authored 26 publications receiving 4030 citations. Previous affiliations of Ghislain Fournous include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
Microbial culturomics: paradigm shift in the human gut microbiome study
Jean-Christophe Lagier,Fabrice Armougom,Matthieu Million,Perrine Hugon,Isabelle Pagnier,Catherine Robert,Fadi Bittar,Ghislain Fournous,Gregory Gimenez,Marie Maraninchi,Jean-François Trape,Eugene V. Koonin,B. La Scola,Didier Raoult +13 more
TL;DR: Culturomics complements metagenomics by overcoming the depth bias inherent in metagenomic approaches, and identifies 174 species never described previously in the human gut.
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The Virophage as a Unique Parasite of the Giant Mimivirus
Bernard La Scola,Christelle Desnues,Isabelle Pagnier,Catherine Robert,Lina Barrassi,Ghislain Fournous,Michèle Merchat,Marie Suzan-Monti,Patrick Forterre,Patrick Forterre,Eugene V. Koonin,Didier Raoult +11 more
TL;DR: The Sputnik genome is an 18.343-kilobase circular double-stranded DNA and contains genes that are linked to viruses infecting each of the three domains of life Eukarya, Archaea and Bacteria and is classified as a virophage.
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Phage as agents of lateral gene transfer.
Carlos Canchaya,Ghislain Fournous,Sandra Chibani-Chennoufi,Marie Lise Dillmann,Harald Brüssow +4 more
TL;DR: Prophages constitute in many bacteria a substantial part of laterally acquired DNA and contribute lysogenic conversion genes that are of selective advantage to the bacterial host.
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The impact of prophages on bacterial chromosomes.
TL;DR: Prophages were automatically localized in se‐quenced bacterial genomes by a simple semantic script leading to the identification of 190 prophages in 115 investigated genomes, and fixation of prophage genes seems to be restricted to those with functions that have been co‐opted by the bacterial host.
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Giant Marseillevirus highlights the role of amoebae as a melting pot in emergence of chimeric microorganisms
Mickaël Boyer,Natalya Yutin,Isabelle Pagnier,Lina Barrassi,Ghislain Fournous,Leon Espinosa,Catherine Robert,Saïd Azza,Siyang Sun,Michael G. Rossmann,Marie Suzan-Monti,Bernard La Scola,Eugene V. Koonin,Didier Raoult +13 more
TL;DR: It is proposed that amoebae are “melting pots” of microbial evolution where diverse forms emerge, including giant viruses with complex gene repertoires of various origins.