G
Giampiero Girolomoni
Researcher at University of Verona
Publications - 565
Citations - 19749
Giampiero Girolomoni is an academic researcher from University of Verona. The author has contributed to research in topics: Psoriasis & Medicine. The author has an hindex of 72, co-authored 502 publications receiving 16506 citations.
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Journal Article
IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha.
TL;DR: The results suggest that IL-17 is an important player of T cell-mediated skin immune responses, with synergistic or antagonist effects on IFN-γ- and TNF-α-stimulated keratinocyte activation.
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Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate-to-severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2).
Carle Paul,J. Cather,Melinda Gooderham,Yves Poulin,Ulrich Mrowietz,Carlos Ferrándiz,Jeffrey J. Crowley,C. Hu,Rm Stevens,K. Shah,Rm Day,Giampiero Girolomoni,Ab Gottlieb +12 more
TL;DR: Apremilast, an oral phosphodiesterase 4 inhibitor, regulates immune responses associated with psoriasis in women and girls with atypical immune responses to chemotherapy.
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Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes.
Cristina Albanesi,Claudia Scarponi,Andrea Cavani,Monica Federici,Francesca Nasorri,Giampiero Girolomoni +5 more
TL;DR: Results indicate that interleukin-17 can participate relevantly in T-cell-mediated skin immune responses by amplifying both interferon-gamma- and interleukain-4-induced activation of keratinocytes.
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Weight loss improves the response of obese patients with moderate-to-severe chronic plaque psoriasis to low-dose cyclosporine therapy: a randomized, controlled, investigator-blinded clinical trial.
TL;DR: Obese patients with moderate-to-severe psoriasis increase their response to low-dose cyclosporine if a calorie-controlled diet is included in the treatment regimen, and lifestyle modifications, including a low-calorie diet, may supplement the pharmacologic treatment of obese Psoriasis patients.
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The interplay between keratinocytes and immune cells in the pathogenesis of psoriasis
TL;DR: The current review emphasizes the aberrant interplay of immune cells and skin-resident keratinocytes in establishing and sustaining inflammatory and immune responses in psoriasis.