G
Gianluca Tosini
Researcher at Morehouse School of Medicine
Publications - 141
Citations - 7691
Gianluca Tosini is an academic researcher from Morehouse School of Medicine. The author has contributed to research in topics: Circadian rhythm & Melatonin. The author has an hindex of 44, co-authored 133 publications receiving 6697 citations. Previous affiliations of Gianluca Tosini include University of Bristol & University of Florence.
Papers
More filters
Journal ArticleDOI
Circadian rhythms in cultured mammalian retina.
Gianluca Tosini,Michael Menaker +1 more
TL;DR: Cultured neural retinas of the golden hamster exhibited circadian rhythms of melatonin synthesis for at least 5 days at 27°C, and retinas from hamsters homozygous for the circadian mutation tau showed a shortened free-running period ofmelatonin synthesis.
Journal ArticleDOI
Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina
P. Michael Iuvone,Gianluca Tosini,Nikita Pozdeyev,Rashidul Haque,David C. Klein,Shyam S. Chaurasia +5 more
TL;DR: This review will cover evidence that cAMP is a major output of the circadian clock in photoreceptor cells; and recent advances indicating that clocks and clock networks occur in multiple cell types of the retina.
Journal Article
Effects of Blue Light on the Circadian System and Eye Physiology
TL;DR: This review summarizes the current knowledge of the effects of blue light on the regulation of physiologic functions and the possible effects ofblue light exposure on ocular health and the spectral output of LED-based light sources to minimize the danger that may be associated with blue light exposure.
Journal ArticleDOI
Update on melatonin receptors: IUPHAR Review 20.
Ralf Jockers,Ralf Jockers,Ralf Jockers,Philippe Delagrange,Margarita L. Dubocovich,Regina P. Markus,Nicolas Renault,Gianluca Tosini,Erika Cecon,Erika Cecon,Erika Cecon,Darius P. Zlotos +11 more
TL;DR: The current review provides an update on melatonin receptors by the corresponding subcommittee of the International Union of Basic and Clinical Pharmacology, and highlights recent developments of melatonin receptor ligands, including radioligands, and gives anupdate on the latest phenotyping results ofmelatonin receptor knockout mice.
Journal ArticleDOI
The clock in the mouse retina: melatonin synthesis and photoreceptor degeneration
Gianluca Tosini,Michael Menaker +1 more
TL;DR: The retinas of some strains of laboratory mice exhibit robust circadian rhythms of melatonin synthesis which can be entrained by light in vitro and the many genetic and molecular tools available in the mouse can now be applied to analysis of the retinal circadian oscillator.