G
Gilles Pagès
Researcher at French Institute of Health and Medical Research
Publications - 403
Citations - 25339
Gilles Pagès is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Quantization (signal processing) & MAPK/ERK pathway. The author has an hindex of 73, co-authored 398 publications receiving 22584 citations. Previous affiliations of Gilles Pagès include Paul Sabatier University & French Institute for Research in Computer Science and Automation.
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Journal ArticleDOI
The telomere proteins in tumorigenesis and clinical outcomes of oral squamous cell carcinoma.
TL;DR: A model encompassing the role of shelterin proteins in oral tumorigenesis and treatment outcome is proposed, which combines telomeres, telomere maintenance, and hallmarks of cancer.
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Pointwise Convergence of the Lloyd I Algorithm in Higher Dimension
Gilles Pagès,Jun Yu +1 more
TL;DR: In this article, the authors established the pointwise convergence of the iterative Lloyd I procedure, also known as the $k$-means algorithm, as soon as the starting grid (with size $N\geq2$) induces a lower mean quadratic quantization error than the minimal mean quantisation error induced by grids of sizes at most $N-1$ with respect to the same input distribution.
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Plk1, upregulated by HIF-2, mediates metastasis and drug resistance of clear cell renal cell carcinoma
Maeva Dufies,Annelies Verbiest,Lindsay S. Cooley,Papa Diogop Ndiaye,Xingkang He,Nicolas Nottet,Wilfried Souleyreau,Anais Hagege,Stéphanie Torrino,Julien Parola,Sandy Giuliano,Delphine Borchiellini,Renaud Schiappa,Baharia Mograbi,Jessica Zucman-Rossi,Karim Bensalah,Alain Ravaud,Patrick Auberger,Andreas Bikfalvi,Emmanuel Chamorey,Nathalie Rioux-Leclercq,Nathalie M. Mazure,Benoit Beuselinck,Yihai Cao,Jean-Christophe Bernhard,Damien Ambrosetti,Gilles Pagès +26 more
TL;DR: In this paper, a hypoxia-regulated mechanism of Plk1-mediated cancer metastasis and drug resistance was uncovered, and a therapeutic paradigm for improving outcomes of ccRCC patients was proposed.
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High-resolution product quantization for Gaussian processes under sup-norm distortion
Harald Luschgy,Gilles Pagès +1 more
TL;DR: In this paper, the authors derived high-resolution upper bounds for optimal product quantization of pathwise contionuous Gaussian processes respective to the supremum norm on [0,T] d.
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AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity
Sanja Brolih,Scott K. Parks,Valérie Vial,Jérôme Durivault,Livio Mostosi,Jacques Pouysségur,Gilles Pagès,Vincent Picco +7 more
TL;DR: It is demonstrated that the alternative action of AKT1 on invasive properties of breast cancers can be extended to head and neck carcinomas, which exhibit constitutive activation of the PI3K/AKT pathway.