scispace - formally typeset
G

Gilles Pagès

Researcher at French Institute of Health and Medical Research

Publications -  403
Citations -  25339

Gilles Pagès is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Quantization (signal processing) & MAPK/ERK pathway. The author has an hindex of 73, co-authored 398 publications receiving 22584 citations. Previous affiliations of Gilles Pagès include Paul Sabatier University & French Institute for Research in Computer Science and Automation.

Papers
More filters
Journal ArticleDOI

Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival

TL;DR: This study represents to the knowledge the first attempt to dissect early global gene transcription occurring in a tumor–stroma coculture model and should help to understand better some of the molecular mechanisms involved in heterotypic signalling between epithelial tumor cells and fibroblasts.
Journal ArticleDOI

Unconstrained recursive importance sampling

TL;DR: In this paper, an unconstrained stochastic approximation method of finding the optimal measure change (in an a priori parametric family) for Monte Carlo simulations is proposed. But this method does not consider the regularity of the density of the law without assume smoothness of the payoff.
Journal ArticleDOI

12-Lipoxygenase and the Regulation of Hypoxia-Inducible Factor in Prostate Cancer Cells

TL;DR: Investigation of the relationship between 12-LOX and hypoxia inducible factor-1 alpha (HIF-1alpha), a transcription factor involved in the regulation of VEGF expression under hypoxic conditions in solid tumors, revealed that Hif-1 is one of the target transcription factors regulated by 12- LOX and 12(S)-HETE, in hypoxic tumor cells of the prostate.
Journal ArticleDOI

The MAPK ERK1 is a negative regulator of the adult steady-state splenic erythropoiesis.

TL;DR: Findings show that ERK1 controls a BMP4-dependent step, regulating the steady state of splenic erythropoiesis, which is shown to require bone morphogenetic protein 4 (BMP4)-dependent signaling in vivo and to rely on the expansion of a resident specialized population of erythroid progenitors, termed stress erythyroid burst-forming units (BFU-Es).
Journal ArticleDOI

Moment estimates for Lévy Processes

TL;DR: For real Levy processes with no Brownian component, the estimate for real Levy process with no Blumenthal-Getoor index has been established by as mentioned in this paper for every $t \in [0, 1]$ and suitable for both $p \leq 2$ and $a_p \in R$.