G
Gina Kim
Researcher at University of Wisconsin-Madison
Publications - 9
Citations - 179
Gina Kim is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Induced pluripotent stem cell & Chemistry. The author has an hindex of 3, co-authored 6 publications receiving 78 citations.
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Journal ArticleDOI
Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
Jianhua Zhang,Ran Tao,Katherine Campbell,Juliana Lott Carvalho,Juliana Lott Carvalho,Edward C. Ruiz,Gina Kim,Eric G. Schmuck,Amish N. Raval,Andre Monteiro da Rocha,Todd J. Herron,José Jalife,José Jalife,James A. Thomson,James A. Thomson,Timothy J. Kamp +15 more
TL;DR: The authors efficiently differentiate human pluripotent stem cells through second heart field progenitors to CFs that exhibit features and functional properties similar to native CFs.
Journal ArticleDOI
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors
Jianhua Zhang,Ran Tao,Katherine Campbell,Juliana Lott Carvalho,Edward C. Ruiz,Gina Kim,Eric G. Schmuck,Amish N. Raval,James A. Thomson,Todd J. Herron,José Jalife,Timothy J. Kamp +11 more
TL;DR: Cardiac fibroblasts play critical roles in heart development, homeostasis, and disease and the sparse availability of human CFs from the native heart limits studies investigating their biology.
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Functionally Integrated Top-Down Proteomics for Standardized Assessment of Human Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues.
Jake A. Melby,Willem J. de Lange,Jianhua Zhang,David S. Roberts,Stanford D. Mitchell,Trisha Tucholski,Gina Kim,Andreas Kyrvasilis,Sean J. McIlwain,Timothy J. Kamp,J. Carter Ralphe,Ying Ge +11 more
TL;DR: In this paper, a 3D human induced pluripotent stem cell-derived engineered cardiac tissues (hiPSC-ECTs) have been used to perform functional and molecular assessments using the same HiPSCECT construct, allowing for more reliable correlation between observed functional performance and underlying molecular events.
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Long QT Syndrome KCNH2 Variant Induces hERG1a/1b Subunit Imbalance in Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Li Feng,Jianhua Zhang,ChangHwan Lee,Gina Kim,Fang Liu,Andrew J. Petersen,Evi Lim,Corey L. Anderson,Kate M. Orland,Gail A. Robertson,Lee L. Eckhardt,Craig T. January,Timothy J. Kamp +12 more
TL;DR: In this paper, patient-specific induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) were derived from a LQT syndrome type 2 (LQT2) patient carrying the PAS domain variant hERG1-H70R.
Journal ArticleDOI
Micropattern platform promotes extracellular matrix remodeling by human PSC‐derived cardiac fibroblasts and enhances contractility of co‐cultured cardiomyocytes
Brett N. Napiwocki,A. Stempien,Di Lang,R.A. Kruepke,Gina Kim,Jianhua Zhang,Lee L. Eckhardt,Alexey V. Glukhov,Timothy J. Kamp,Wendy C. Crone +9 more
TL;DR: In this paper, a 2D in vitro micropatterned platform that provides control over ECM geometry and substrate stiffness was used to provide more representative in vitro cardiac constructs.