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Giorgio Soldani

Researcher at National Research Council

Publications -  56
Citations -  1616

Giorgio Soldani is an academic researcher from National Research Council. The author has contributed to research in topics: Wound healing & Fibrin. The author has an hindex of 20, co-authored 51 publications receiving 1371 citations. Previous affiliations of Giorgio Soldani include Brown University.

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Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice

TL;DR: The ability of the scaffold/GF-loaded NPs to promote wound healing in a diabetic mouse model suggests its potential use as a dressing in patients with diabetic foot ulcers.
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Long term performance of small-diameter vascular grafts made of a poly(ether)urethane-polydimethylsiloxane semi-interpenetrating polymeric network.

TL;DR: Assessment of the blood and tissue compatibility behaviors of a novel compliant SDVGs fabricated with a poly(ether)urethane-polydimethylsiloxane (PEtU-PDMS) semi-interpenetrating polymeric network (semi-IPN) and featuring two different porous layers in the wall thickness showed superior handling and compliance characteristics, and patency rates of PEtU -PDMS grafts in comparison with a standard ePTFE graft.
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Effect of platelet lysate on human cells involved in different phases of wound healing.

TL;DR: The possibility of using allogeneic platelet lysate as both an alternative to growth factors commonly used for cell culture and as a tool for clinical regenerative application for wound healing is suggested.
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Glubran2 Surgical Glue: In Vitro Evaluation of Adhesive and Mechanical Properties

TL;DR: All tests showed the intrinsic tensile strength of polymerized Glubran2 and its capability to realize a higher-resistance bonding among biologic tissues, in comparison with fibrin glue, giving strong indication of its usefulness in surgical and endoscopic practice, especially in a wet environment.
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Tissue response to poly(ether)urethane-polydimethylsiloxane-fibrin composite scaffolds for controlled delivery of pro-angiogenic growth factors.

TL;DR: It is shown that the semi-IPN composite scaffold acting as a pro-angiogenic GFs delivery system has therapeutic potential for the local treatment of ischemic tissue and wound healing.