Giovanni N. Roviello

TL;DR: Various approaches recently proposed in the literature to inhibit HMGB1 and the related inflammatory processes are described, especially focusing on the block of RAGE-HMGB1 signaling.

TL;DR: Since the recoveries/deaths ratio in the last weeks significantly increased, especially in China, it is clear that the experimental antiviral therapy, together with the availability of intensive care unit beds in hospitals and rigorous government control measures, all play an important role in dealing with this virus.

TL;DR: Recent advancements in SELEX technology for the efficient and rapid identification of new candidate aptamers (introduction of microfluidic systems and next generation sequencing) and discovery of several G4-forming motifs in important regulatory regions of the human or viral genome bound by endogenous proteins are reviewed.

TL;DR: It is suggested that evergreen Mediterranean forests and shrubland plants could have protected the southern population by emission of immuno-modulating VOCs and provision of dietary sources of bioactive compounds.

TL;DR: In this paper, the potential role of clove in the frame of anti-COVID-19 therapy, focusing on the antiviral, anti-inflammatory, and antithrombotic effects of Clove and its molecular constituents described in the scientific literature.