Giovanni Taibbi

TL;DR: Results from head-down bed-rest studies and from parabolic flight experiments indicate that ocular blood flow and intraocular pressure may undergo changes in a low-gravity environment, and suggest changes in translaminar pressure may be implicated in the pathophysiology of optic disk neuropathies.

TL;DR: The HDT BR duration may be critical for replicating microgravity-related ophthalmologic changes observed in astronauts on ≥6-month spaceflights, suggesting that time may affect the amount of optic disc swelling.

TL;DR: Investigation of possible mechanisms for ocular changes in eight male subjects during three 1‐h conditions found acute exposure to mild hypercapnia during HDT did not augment cardiovascular outcomes, ICP, or TLPD relative to the HDT condition.

TL;DR: In this work, several factors affecting Cirrus HD-OCT optic disc scan quality and their effects on measurement variability are described and described.

TL;DR: A few functional and structural changes were detected after 14-d HDTBR, notably an improved BCVA possibly due to learning effect and RNFL thickening without signs of optic disc edema, and further studies with different BR duration and/or tilt angle are warranted to investigate microgravity-induced ophthalmological changes.