G
Giridhar R. Akkaraju
Researcher at University of Texas at Dallas
Publications - 5
Citations - 2088
Giridhar R. Akkaraju is an academic researcher from University of Texas at Dallas. The author has contributed to research in topics: Medicine & Quantum dot. The author has an hindex of 1, co-authored 1 publications receiving 1948 citations.
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TAK1 is a ubiquitin-dependent kinase of MKK and IKK
TL;DR: The purification and identification of TRIKA2, which is composed of TAK1, TAB1 and TAB2, a protein kinase complex previously implicated in IKK activation through an unknown mechanism, indicate that ubiquitination has an important regulatory role in stress response pathways, including those of IKK and JNK.
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Detection of Pancreatic Cancer miRNA with Biocompatible Nitrogen-Doped Graphene Quantum Dots
Ryan Ajgaonkar,Bong Han Lee,Alina Valimukhametova,Steven Nguyen,Roberto Gonzalez-Rodriguez,Jeffery L. Coffer,Giridhar R. Akkaraju,Anton V. Naumov +7 more
TL;DR: The presence of a specific pancreatic cancer-derived miRNA (pre-miR-132) is detected using the fluorescence properties of biocompatible nitrogen-doped graphene quantum dots (NGQDs) synthesized using a bottom-up approach from a single glucosamine precursor.
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Dual-Mode Fluorescence/Ultrasound Imaging with Biocompatible Metal-Doped Graphene Quantum Dots.
Alina Valimukhametova,Olga S Zub,Bong Han Lee,Olivia Fannon,Steven Nguyen,Roberto Gonzalez-Rodriguez,Giridhar R. Akkaraju,Anton V. Naumov +7 more
TL;DR: A combination of non-invasive ultrasound imaging with capabilities of high-precision fluorescence tracking makes these metal-doped NGQDs a viable agent for a variety of theragnostic applications.
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In Vitro Prostate Cancer Treatment via CRISPR‐Cas9 Gene Editing Facilitated by Polyethyleneimine‐Derived Graphene Quantum Dots
Bong Han Lee,Alina Valimukhametova,Ryan Lee McKinney,Roberto Gonzalez-Rodriguez,U. C. Topkıran,Jeffery L. Coffer,Giridhar R. Akkaraju,Anton V. Naumov +7 more
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Cancer Therapeutic siRNA Delivery and Imaging by Nitrogen- and Neodymium-Doped Graphene Quantum Dots.
Alina Valimukhametova,Bong Han Lee,U. C. Topkıran,Roberto Gonzalez-Rodriguez,Jeffery L. Coffer,Giridhar R. Akkaraju,Anton V. Naumov +6 more
TL;DR: In this article , a biocompatible nitrogen-and neodymium-doped graphene quantum dot (NGQD) was used for the delivery of Kirsten rat sarcoma virus (KRAS) and epidermal growth factor receptor (EGFR) siRNA effective against a variety of cancer types.