Gisela Nogales-Gadea

TL;DR: This study provides Class IV evidence that autoantibodies to NF155 identify a CIDP subtype characterized by severe neuropathy, poor response to IVIg, and disabling tremor.

TL;DR: Examination of the reactivity of CIDP patients' sera against neuronal antigens and immunoprecipitation for antigen unraveling found no evidence of autoantibodies being involved in its pathogenesis.

TL;DR: I Illa et al. as mentioned in this paper designed an unbiased approach for antigen unraveling using patients9 sera for hippocampal neuron immunoprecipitation, which revealed the presence of antibodies against CNTN1 complex proteins in a small subset of CIDP patients sharing specific clinical features.

TL;DR: The topics covered include diagnostic tools— for example, molecular genetic diagnosis, the classic ischemic forearm test and the so-called 'second wind' phenomenon—and current therapeutic options—for example, a carbohydrate-rich diet and carbohydrate ingestion shortly before strenuous exercise, in combination with medically supervised aerobic training of low to moderate intensity.

TL;DR: The main clinical features of McArdle disease are generally homogeneous and frequently appear during childhood; clinical condition deteriorates with ageing; active patients have a better clinical outcome and functional capacity.