G
Giuseppe Attardi
Researcher at California Institute of Technology
Publications - 238
Citations - 24344
Giuseppe Attardi is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Mitochondrial DNA & Mitochondrion. The author has an hindex of 77, co-authored 237 publications receiving 23615 citations. Previous affiliations of Giuseppe Attardi include Scripps Health & University of Bari.
Papers
More filters
Journal ArticleDOI
tRNA punctuation model of RNA processing in human mitochondria
TL;DR: It is proposed that the H strand is transcribed into a single polycistronic RNA molecule, which is processed later into mature species by precise endonucleolytic cleavages which occur, in most cases, immediately before and after a tRNA sequence.
Journal ArticleDOI
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation
Michael P. King,Giuseppe Attardi +1 more
TL;DR: Transformants obtained with various mitochondrial donors exhibited a respiratory phenotype that was in most cases distinct from that of the rho 0 parent or the donor, indicating that the genotypes of the mitochondrial and nuclear genomes as well as their specific interactions play a role in the respiratory competence of a cell.
Journal ArticleDOI
Biogenesis of Mitochondria
TL;DR: The MITOCHONDRIAL GENETIC SYSTEM, a chronology of key events and events leading to and after the invention of the mitochondria, is described.
Journal ArticleDOI
Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication.
TL;DR: Examination of mtDNA revealed high copy point mutations at specific positions in the control region for replication of human fibroblast mtDNA from normal old, but not young, individuals.
Journal ArticleDOI
Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase
Anne Chomyn,Paolo Mariottini,M. W. J. Cleeter,CI Ragan,Akemi Matsuno-Yagi,Youssef Hatefi,Russell F. Doolittle,Giuseppe Attardi +7 more
TL;DR: It is concluded that the six reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase.