G
Giuseppe Broggi
Researcher at University of Catania
Publications - 125
Citations - 938
Giuseppe Broggi is an academic researcher from University of Catania. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 9, co-authored 60 publications receiving 307 citations.
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Journal ArticleDOI
CircSMARCA5 Regulates VEGFA mRNA Splicing and Angiogenesis in Glioblastoma Multiforme Through the Binding of SRSF1.
Davide Barbagallo,Angela Caponnetto,Duilia Brex,Federica Mirabella,Cristina Barbagallo,Giovanni Lauretta,Antonio Morrone,Francesco Certo,Giuseppe Broggi,Rosario Caltabiano,Giuseppe Barbagallo,Vittoria Spina-Purrello,Marco Ragusa,Cinzia Di Pietro,Thomas B. Hansen,Michele Purrello +15 more
TL;DR: The data convincingly suggest that circSMARCA5 is an upstream regulator of pro- to anti-angiogenic VEGFA isoforms ratio within GBM cells and a highly promising GBM prognostic and prospective anti-Angiogenic molecule.
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Serum Extracellular Vesicle-Derived circHIPK3 and circSMARCA5 Are Two Novel Diagnostic Biomarkers for Glioblastoma Multiforme.
Michele Stella,Luca Falzone,Angela Caponnetto,Giuseppe Gattuso,Cristina Barbagallo,Rosalia Battaglia,Federica Mirabella,Giuseppe Broggi,Roberto Altieri,Francesco Certo,Rosario Caltabiano,Giuseppe Barbagallo,Paolo Musumeci,Marco Ragusa,Cinzia Di Pietro,Massimo Libra,Michele Purrello,Davide Barbagallo +17 more
TL;DR: In this article, the authors suggest the use of serum extracellular vesicle (sEV)-derived circular RNAs (circRNAs) as highly stable minimally invasive diagnostic biomarkers for GBM diagnosis.
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The GAUGAA Motif Is Responsible for the Binding between circSMARCA5 and SRSF1 and Related Downstream Effects on Glioblastoma Multiforme Cell Migration and Angiogenic Potential.
Davide Barbagallo,Angela Caponnetto,Cristina Barbagallo,Rosalia Battaglia,Federica Mirabella,Duilia Brex,Michele Stella,Giuseppe Broggi,Roberto Altieri,Francesco Certo,Rosario Caltabiano,Giuseppe Barbagallo,Carmelina Daniela Anfuso,Gabriella Lupo,Marco Ragusa,Cinzia Di Pietro,Thomas B. Hansen,Michele Purrello +17 more
TL;DR: In this paper, the authors characterized RNA motifs functionally involved in the interaction between circSMARCA5 and SRSF1 through six predicted binding sites (BSs) based on the RNA immunoprecipitation assay.
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FLAIRectomy in Supramarginal Resection of Glioblastoma Correlates With Clinical Outcome and Survival Analysis: A Prospective, Single Institution, Case Series.
Francesco Certo,Roberto Altieri,Massimiliano Maione,Claudio Schonauer,Giuseppe Sortino,Giuseppa Fiumanò,Elena Tirrò,Michele Massimino,Giuseppe Broggi,Paolo Vigneri,Gaetano Magro,Massimiliano Visocchi,Giuseppe Barbagallo +12 more
TL;DR: FLAIR-based EOTR appears to be a stronger survival predictor compared to gadolinium-enhancing, T1-based resection, and eOTR based on FLAIR and 5-ALA fluorescence is feasible.
Journal ArticleDOI
Peritumoral Microenvironment in High-Grade Gliomas: From FLAIRectomy to Microglia–Glioma Cross-Talk
Roberto Altieri,Davide Barbagallo,Francesco Certo,Giuseppe Broggi,Marco Ragusa,Cinzia Di Pietro,Rosario Caltabiano,Gaetano Magro,Simone Peschillo,Michele Purrello,Giuseppe Barbagallo +10 more
TL;DR: The role of peritumoral area in high grade gliomas from surgical and biological points of view is summarized in this paper. But the role of microglia in HGGs is not discussed in this paper.