Giuseppe Lauria

TL;DR: The frequency of painful polyneuropathy is shown and it is demonstrated that this difficult-to-treat complication is more common in women than in men, with female sex as the only risk factor for suffering from painful polynuropathy.

TL;DR: A 66-year-old woman admitted to hospital on November 12, 2001, because of 5 months of visual disturbances and slight gait unbalance experienced a sudden worsening of symptoms with dysarthria, dysphagia, inability to stand and walk without assistance, pronounced trunk ataxia, all-limb dysmetria, leg spasticity, increased deep-tendon reflexes, and bilateral Babinski sign.

TL;DR: Investigation of chronic progressive ganglionopathy of different etiology found a widespread decrease in sensory nerve action potential amplitudes, which involved both upper and lower limb nerves, even in patients with asymmetrical or patchy clinical presentation.

TL;DR: In this article, the usefulness and limitations of skin biopsy and the relationship between degeneration and regeneration of small nerve fibers in patients with diabetes and metabolic syndrome are discussed. But, the diagnosis of small fiber neuropathy is challenging in clinical practice.

TL;DR: Potentially pathogenic VGSC variants are present in 11.6% of patients with pure SFN and genetic screening of SCN9A, SCN10A and SCN11A should be considered in patients withpure SFN, independently of clinical features or underlying conditions.