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Giuseppe Ristagno

Researcher at Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Publications -  248
Citations -  6639

Giuseppe Ristagno is an academic researcher from Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. The author has contributed to research in topics: Cardiopulmonary resuscitation & Resuscitation. The author has an hindex of 35, co-authored 223 publications receiving 5197 citations. Previous affiliations of Giuseppe Ristagno include Mario Negri Institute for Pharmacological Research & Weil, Gotshal & Manges.

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Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

TL;DR: The findings point to uromodulin as a therapeutic target for lowering blood pressure and preserving renal function and the relevance of this mechanism in humans is demonstrated by showing that pharmacological inhibition of NKCC2 was more effective in lowering blood pressured patients who are homozygous for UMOD promoter risk variants than in other hypertensive patients.
Journal ArticleDOI

Epinephrine reduces cerebral perfusion during cardiopulmonary resuscitation.

TL;DR: In this model, epinephrine through its &agr;1-agonist action had adverse effects on cerebral microvascular blood flow such as to increase the severity of cerebral ischemia during CPR.