G
Giuseppe Tridente
Researcher at University of Verona
Publications - 151
Citations - 2757
Giuseppe Tridente is an academic researcher from University of Verona. The author has contributed to research in topics: Antigen & Immunotoxin. The author has an hindex of 29, co-authored 150 publications receiving 2650 citations.
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In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes.
Giovanna Zanoni,Riccardo Navone,Claudio Lunardi,Giuseppe Tridente,Caterina Bason,Simona Sivori,Ruggero Beri,Marzia Dolcino,Enrico Valletta,Roberto Corrocher,Antonio Puccetti +10 more
TL;DR: In active celiac disease, a subset of anti-transglutaminase IgA antibodies recognize the viral protein VP-7, suggesting a possible involvement of rotavirus infection in the pathogenesis of the disease, through a mechanism of molecular mimicry.
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Immune Regulation by Mesenchymal Stem Cells Derived from Adult Spleen and Thymus
Mauro Krampera,Silvia Sartoris,Francesco Liotta,Annalisa Pasini,Roberta Angeli,Lorenzo Cosmi,Angelo Andreini,Federico Mosna,Bruno Bonetti,Elisabetta Rebellato,Maria Grazia Testi,Francesca Frosali,Giovanni Pizzolo,Giuseppe Tridente,Enrico Maggi,Sergio Romagnani,Francesco Annunziato +16 more
TL;DR: It is suggested that not only do spleen and thymus have a stem cell reservoir to build up their stromal architecture, but also contain microenviromental immunoregulatory cells with the same properties of BM-MSCs.
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Anti-tumor effects of toxins targeted to the prostate specific membrane antigen.
Giulio Fracasso,G. Bellisola,Sara Cingarlini,Deborah Castelletti,Tommaso Prayer-Galetti,Francesco Pagano,Giuseppe Tridente,Marco Colombatti +7 more
TL;DR: Immunotherapy with monoclonal antibody–vehicled toxins (Immunotoxins, ITs) may be a promising novel treatment option for the management of prostate cancer in cases of relapsing, metastatic, androgen‐independent prostate cancer.
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IFN-gamma-mediated upmodulation of MHC class I expression activates tumor-specific immune response in a mouse model of prostate cancer.
Matteo Martini,Maria Grazia Testi,Matteo Pasetto,Maria Cristina Picchio,Giulio Innamorati,Marta Mazzocco,Stefano Ugel,Sara Cingarlini,Vincenzo Bronte,Paola Zanovello,Mauro Krampera,Federico Mosna,Tiziana Cestari,Anna Pia Riviera,N. Brutti,Ottavia Barbieri,Lina Matera,Giuseppe Tridente,Marco Colombatti,Silvia Sartoris +19 more
TL;DR: In this article, a mouse prostate adenocarcinoma (TRAMP-C2/B7) was treated with IFN-γ, which increased MHC-I expression by induction of some APM components and antagonizing the immunosuppressant activity of TGF-β.
Journal ArticleDOI
The Prostate Specific Membrane Antigen Regulates the Expression of IL-6 and CCL5 in Prostate Tumour Cells by Activating the MAPK Pathways1
Marco Colombatti,Silvia Grasso,Alessandra Porzia,Giulio Fracasso,Maria Teresa Scupoli,Sara Cingarlini,Ornella Poffe,Hassan Y. Naim,Martin Heine,Giuseppe Tridente,Fabrizio Mainiero,Dunia Ramarli +11 more
TL;DR: The novel functions attributable to PSMA may have profound influence on the survival and proliferation of prostate tumor cells, accounting for the observation that PSMA overexpression in prostate cancer patients is related to a worse prognosis.