Gordon G. Simpson

TL;DR: An integrated network of pathways that quantitatively control the timing of this developmental switch in Arabidopsis are identified and this framework provides the basis to understand the evolution of different reproductive strategies and how floral pathways interact through seasonal progression.

TL;DR: For future RNA-seq experiments, results suggest that at least six biological replicates should be used, rising to at least 12 when it is important to identify SDE genes for all fold changes, and if fewer than 12 replicates are used, a superior combination of true positive and false positive performances makes edgeR and DESeq2 the leading tools.

TL;DR: Associated with the changes in lignin, the conversion of cellulose to glucose in cse mutants increased up to fourfold as compared to that in the wild type upon saccharification without pretreatment, which necessitate the revision of currently accepted models of the lign in biosynthetic pathway.

TL;DR: It is proposed that FCA controls 3' end formation of specific transcripts and that in higher eukaryotes, proteins homologous to FY may have evolved as sites of association for regulators of RNA3' end processing.

TL;DR: In this article, an RNA-seq experiment with 48 biological replicates in each of 2 conditions was performed to determine the number of biological replication required to identify the most effective statistical analysis tools for identifying differential gene expression (DGE).