R
Ruben Vanholme
Researcher at Ghent University
Publications - 61
Citations - 6470
Ruben Vanholme is an academic researcher from Ghent University. The author has contributed to research in topics: Lignin & Lignocellulosic biomass. The author has an hindex of 26, co-authored 54 publications receiving 5060 citations. Previous affiliations of Ruben Vanholme include Flanders Institute for Biotechnology.
Papers
More filters
Journal ArticleDOI
Lignin Biosynthesis and Structure
TL;DR: Lignin is the generic term for a large group of aromatic polymers resulting from the oxidative combinatorial coupling of 4-hydroxyphenylpropanoids, deposited predominantly in the walls of secondarily thickened cells, making them lignin-like polymers.
Journal ArticleDOI
Reductive lignocellulose fractionation into soluble lignin-derived phenolic monomers and dimers and processable carbohydrate pulps
S. Van den Bosch,Wouter Schutyser,Ruben Vanholme,T. Driessen,S.-F. Koelewijn,Tom Renders,B. De Meester,Wouter J. J. Huijgen,Wim Dehaen,Christophe M. Courtin,Bert Lagrain,Wout Boerjan,Bert F. Sels +12 more
TL;DR: In this paper, a catalytic lignocellulose biorefinery process is presented, valorizing both polysaccharide and lignin components into a handful of chemicals.
Journal ArticleDOI
Caffeoyl Shikimate Esterase (CSE) Is an Enzyme in the Lignin Biosynthetic Pathway in Arabidopsis
Ruben Vanholme,Ruben Vanholme,Igor Cesarino,Igor Cesarino,Katarzyna Rataj,Yuguo Xiao,Lisa Sundin,Lisa Sundin,Geert Goeminne,Geert Goeminne,Hoon Kim,Joanna Cross,Joanna Cross,Kris Morreel,Kris Morreel,Pedro Araújo,Pedro Araújo,Lydia Welsh,Jurgen Haustraete,Christopher McClellan,Bartel Vanholme,Bartel Vanholme,John Ralph,Gordon G. Simpson,Claire Halpin,Wout Boerjan,Wout Boerjan +26 more
TL;DR: Associated with the changes in lignin, the conversion of cellulose to glucose in cse mutants increased up to fourfold as compared to that in the wild type upon saccharification without pretreatment, which necessitate the revision of currently accepted models of the lign in biosynthetic pathway.
Journal ArticleDOI
Lignin biosynthesis and its integration into metabolism.
TL;DR: Upon perturbation of the phenylpropanoid pathway, pathway intermediates may successfully incorporate into the lignin polymer, thereby affecting its physicochemical properties, or may remain soluble as such or as derivatized molecules that might interfere with physiological processes.
Journal ArticleDOI
Metabolic engineering of novel lignin in biomass crops
Ruben Vanholme,Kris Morreel,Chiarina Darrah,Paula Oyarce,John H. Grabber,John Ralph,Wout Boerjan +6 more
TL;DR: The status of detection and identification of compounds by Phenolic profiling is discussed, as phenolic profiling serves in pathway elucidation and for the detection of incorporation of alternative lignin monomers.