Grace Yoon

TL;DR: It is shown that hair follicle mesenchymal progenitors make limited contributions to wound repair, and pharmacological modulation of RUNX1 and retinoic acid signaling or genetic deletion of Hic1 within wound-activated fibroblasts was sufficient to modulate healing outcomes, suggesting that reparative fibro Blasts have latent but modifiable regenerative capacity.

TL;DR: Interestingly, impairment in both macrophage accumulation and functional recovery could be overcome by transplanting bone marrow from aged animals into young mice, and the data suggest that age-associated defects in MCP1 signaling could contribute to the regenerative deficits that occur in the aged nervous system.

TL;DR: C cultured DPCs were transplanted into a full-thickness skin wound in immune-compromised mice and closed with a human STSG, improving both viscoelastic properties of the graft and mitigating pruritus.

TL;DR: This investigation identifies a demographical profile where electrical burns account for a significant percentage of the burn population in the Dominican Republic, providing a basis for concentrating preventative efforts in vulnerable populations.

TL;DR: Characterize burn CTs by analyzing location, completion status, temporal trend, and funding sources and assess quality of trial reporting to reduce precocious termination and mandatory reporting of data fields can improve quality of reporting.