G
Graeme J. Nicholson
Researcher at University of Tübingen
Publications - 111
Citations - 6514
Graeme J. Nicholson is an academic researcher from University of Tübingen. The author has contributed to research in topics: Enantiomer & Amino acid. The author has an hindex of 42, co-authored 111 publications receiving 6217 citations.
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Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine
Andreas Peschel,Andreas Peschel,Ralph W. Jack,Michael Otto,L. Vincent Collins,Petra Staubitz,Graeme J. Nicholson,Hubert Kalbacher,Willem F. Nieuwenhuizen,Günther Jung,Andrej Tarkowski,Kok P. M. van Kessel,Jos A. G. van Strijp +12 more
TL;DR: A novel staphylococcal gene, mprF, which determines resistance to several host defense peptides such as defensins and protegrins constitutes a novel virulence factor, which may be of general relevance for bacterial pathogens and represents a new target for attacking multidrug resistant bacteria.
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Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections
Christopher Weidenmaier,John F. Kokai-Kun,Sascha A. Kristian,Tanya Chanturiya,Hubert Kalbacher,Matthias Gross,Graeme J. Nicholson,Birgid Neumeister,James J. Mond,Andreas Peschel +9 more
TL;DR: It is shown that wall teichoic acid (WTA), a surface-exposed staphylococcal polymer, is essential for nasal colonization and mediates interaction with human nasal epithelial cells.
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Rapid gas chromatographic separation of amino acid enantiomers with a novel chiral stationary phase.
TL;DR: The use of novel polysiloxanes as stationary phase carrying chiral groups enables the separation of most amino acid enantiomers in a much shorter time than ever reported previously.
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Recent advances in capillary electrophoresis/electrospray-mass spectrometry.
TL;DR: In this review, the progress in hyphenation of capillary electrophoresis (CE) with electrospray ionization‐mass spectrometry (ESI‐MS) since the article of Banks (Banks, J. F., Electrophoresi 1997, 18, 2255–2266) is reported.
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The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica.
Bojan Bister,Daniel Bischoff,Graeme J. Nicholson,Marianne Valdebenito,Kathrin Schneider,Günther Winkelmann,Klaus Hantke,Roderich D. Süssmuth +7 more
TL;DR: A detailed analysis proved iroB to be the sole gene with glycosyltransferase activity necessary for salmochelin production and comparison of partial structures of salmochelins with a C-glycosylated compound previously characterized by another group strongly suggest that salmOChelins represent the long sought compounds termed Salmonella resistance factors (SRF) or pacifarins.