Ralph W. Jack

TL;DR: A role of thed-alanine-esterified teichoic acids which occur in many pathogenic bacteria in the protection against human and animal defense systems is proposed.

TL;DR: A novel staphylococcal gene, mprF, which determines resistance to several host defense peptides such as defensins and protegrins constitutes a novel virulence factor, which may be of general relevance for bacterial pathogens and represents a new target for attacking multidrug resistant bacteria.

TL;DR: HHD mice provide a versatile animal model for preclinical evaluation of peptide‐based cancer immunotherapy and CTL responses against five distinct epitopes could be elicited simultaneously in a single animal.

TL;DR: The results suggest that exosome release is not R constitutive activity of B cells, but may be induced following cell: cell signaling, and a link between the BCR and this exocytic pathway is demonstrated.

TL;DR: In vitro studies with microcin B17 have helped to uncover the molecular mechanisms by which post-translational modification results in the formation of heterocyclic oxazole and thiazole rings, and the identification of the 'docking molecules' represents a step forward in the search for novel targets for future antibiosis.