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Andreas Peschel

Researcher at University of Tübingen

Publications -  228
Citations -  21972

Andreas Peschel is an academic researcher from University of Tübingen. The author has contributed to research in topics: Staphylococcus aureus & Teichoic acid. The author has an hindex of 74, co-authored 213 publications receiving 19083 citations. Previous affiliations of Andreas Peschel include Brigham and Women's Hospital & Utrecht University.

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Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides.

TL;DR: A role of thed-alanine-esterified teichoic acids which occur in many pathogenic bacteria in the protection against human and animal defense systems is proposed.
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The co-evolution of host cationic antimicrobial peptides and microbial resistance

TL;DR: It is proposed that CAMPs and CAMP-resistance mechanisms have co-evolved, leading to a transient host–pathogen balance that has shaped the existing CAMP repertoire.
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Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine

TL;DR: A novel staphylococcal gene, mprF, which determines resistance to several host defense peptides such as defensins and protegrins constitutes a novel virulence factor, which may be of general relevance for bacterial pathogens and represents a new target for attacking multidrug resistant bacteria.
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Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions

TL;DR: Identifying and harnessing highly conserved or species-specific structural features of CWGs offers excellent opportunities for developing new antibiotics, vaccines and diagnostics for use in the fight against severe infectious diseases, such as sepsis, pneumonia, anthrax and tuberculosis.