G
Graham Sandford
Researcher at Durham University
Publications - 234
Citations - 3888
Graham Sandford is an academic researcher from Durham University. The author has contributed to research in topics: Nucleophile & Pyridine. The author has an hindex of 34, co-authored 233 publications receiving 3578 citations. Previous affiliations of Graham Sandford include Government of the United Kingdom & GlaxoSmithKline.
Papers
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Iodination of deactivated aromatics with N-iodosuccinimide in trifluoromethanesulfonic acid (NIC-CF3SO3H) via in situ generated superelectrophilic iodine(I) trifluoromethanesulfonate
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Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes
Satoshi Mizuta,I S Stenhagen,Miriam L. O’Duill,Jamie R. Wolstenhulme,Anna K. Kirjavainen,S J Forsback,Matthew Tredwell,Graham Sandford,P R Moore,Mickael Huiban,S K Luthra,Jan Passchier,Olof Solin,Gouverneur +13 more
TL;DR: Treatment of readily available α,α-difluoro- and α-fluoroarylacetic acids with Selectfluor under Ag(I) catalysis led to decarboxylative fluorination, giving access to tri- and difluoromethylarenes applying a late-stage fluorination strategy.
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Organofluorine chemistry: applications, sources and sustainability
Antal Harsanyi,Graham Sandford +1 more
TL;DR: Fluorine is an essential element for life in the developed world that impacts hugely on the general public because many pharmaceuticals, agrochemicals, anaesthetics, materials and air conditioning materials owe their important properties to the presence of fluorine atoms within their structures as discussed by the authors.
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Elemental fluorine. Part 13. Gas-liquid thin film microreactors for selective direct fluorination.
TL;DR: Continuous flow gas-liquid thin film microreactors have been effectively used for the selective fluorination of a range of 1,3-dicarbonyl and aromatic substrates and the conversion of aromatic disulfides to the corresponding sulfur pentafluorides.
Journal ArticleDOI
Radiosynthesis and Evaluation of [18F]Selectfluor bis(triflate)†
Harriet Teare,Edward G. Robins,Anna K. Kirjavainen,Sarita Forsback,Graham Sandford,Olof Solin,Sajinder K. Luthra,Véronique Gouverneur +7 more
TL;DR: Positron (b) emission tomography (PET) is a noninvasive molecular imaging technique that allows for the in vivo investigation of physiological processes and electrophilic F-fluorination suffers from well-recognized drawbacks.