O
Olof Solin
Researcher at Åbo Akademi University
Publications - 256
Citations - 11280
Olof Solin is an academic researcher from Åbo Akademi University. The author has contributed to research in topics: Glucose uptake & Putamen. The author has an hindex of 60, co-authored 243 publications receiving 10517 citations. Previous affiliations of Olof Solin include Imperial College London & Pomeranian Medical University.
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Journal ArticleDOI
Presynaptic dopamine function in striatum of neuroleptic-naive schizophrenic patients
Jarmo Hietala,Erkka Syvälahti,Mikko Kuoppamäki,Merja Haaparanta,Ulla Ruotsalainen,K. Vuorio,V. Räkköläinen,J. Bergman,Olof Solin,Olli Kirvelä,Raimo K. R. Salokangas +10 more
TL;DR: Alterations in striatal presynaptic dopamine function may constitute a part of disrupted neural circuits that predispose to schizophrenic psychosis.
Journal ArticleDOI
Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study.
Juha O. Rinne,Raija Portin,H M Ruottinen,Elina Nurmi,Jörgen Bergman,Merja Haaparanta,Olof Solin +6 more
TL;DR: Reduced [18F] fluorodopa uptake in PD in the caudate nucleus (and frontal cortex) is related to impairment in neuropsychologic tests measuring verbal fluency, working memory, and attentional functioning reflecting frontal lobe function.
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Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo.
Pirjo Nuutila,Veikko A. Koivisto,Juhani Knuuti,Ulla Ruotsalainen,Mika Teräs,Merja Haaparanta,J. Bergman,Olof Solin,Liisa-Maria Voipio-Pulkki,U. Wegelius +9 more
TL;DR: The data demonstrate that the glucose-FFA cycle operates in vivo in both heart and skeletal muscles in humans.
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An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome
H M Ruottinen,Markku Partinen,Christer Hublin,Jörgen Bergman,Merja Haaparanta,Olof Solin,Juha O. Rinne +6 more
TL;DR: Investigation of patients with periodic limb movement disorder and restless legs syndrome and healthy controls with PET using 6-[18F]fluoro-l-dopa indicates mild nigrostriatal presynaptic dopaminergic hypofunction in PLMD-RLS, indicating equal affection of the caudate and the putamen.
Journal ArticleDOI
Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophrenia
Jarmo Hietala,Erkka Syvälahti,Harry Vilkman,K. Vuorio,V. Räkköläinen,Jörgen Bergman,Merja Haaparanta,Olof Solin,Mikko Kuoppamäki,Esa Eronen,Ulla Ruotsalainen,Raimo K. R. Salokangas +11 more
TL;DR: The major finding in this study is that depressive symptoms in neuroleptic-naive first-admission schizophrenia are associated with low presynaptic dopamine function, which appears to be hemisphere-related and may have drug-treatment implications, e.g., in prediction of response to D2 receptor blocking antipsychotic drugs.