G
Grainne D'Ancona
Researcher at Guy's and St Thomas' NHS Foundation Trust
Publications - 46
Citations - 638
Grainne D'Ancona is an academic researcher from Guy's and St Thomas' NHS Foundation Trust. The author has contributed to research in topics: Benralizumab & Mepolizumab. The author has an hindex of 9, co-authored 40 publications receiving 253 citations. Previous affiliations of Grainne D'Ancona include King's College London & Guy's Hospital.
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Journal ArticleDOI
Real-World Effectiveness of Benralizumab in Severe Eosinophilic Asthma.
Joanne Kavanagh,Andrew P. Hearn,Jaideep Dhariwal,Grainne D'Ancona,Abdel Douiri,Cris Roxas,Mariana Fernandes,Linda K. Green,L Thomson,Alexandra M. Nanzer,Brian D. Kent,David A. Jackson +11 more
TL;DR: In a large real-world SEA cohort, benralizumab led to significant improvements in all clinical outcome measures and the optimal regression model of super-responders versus other responders included baseline characteristics associated with a strongly eosinophilic phenotype and less severe disease.
Journal ArticleDOI
Real-World Effectiveness and the Characteristics of a "Super-Responder" to Mepolizumab in Severe Eosinophilic Asthma.
Joanne Kavanagh,Grainne D'Ancona,Maria Elstad,L. Green,Mariana Fernandes,L Thomson,Cris Roxas,Jaideep Dhariwal,AM Nanzer,Brian D. Kent,David A. Jackson,David A. Jackson +11 more
TL;DR: In a real-world SEA cohort, treatment with mepolizumab reduced exacerbation frequency and mOCS requirements and Nasal polyposis, a lower BMI and a lower maintenance prednisolone requirement at baseline were associated with better outcomes.
Journal ArticleDOI
Adherence to corticosteroids and clinical outcomes in mepolizumab therapy for severe asthma
Grainne D'Ancona,Joanne Kavanagh,Cris Roxas,L. Green,Mariana Fernandes,L Thomson,Jaideep Dhariwal,Alexandra M. Nanzer,David A. Jackson,Brian D. Kent +9 more
TL;DR: Poor adherence to ICS is common in severe asthma patients receiving mepolizumab, and is associated with increased oral corticosteroid exposure and exacerbation risk, as well as a lesser reduction in OCS requirements and AER.
Journal ArticleDOI
NREM parasomnias: a treatment approach based upon a retrospective case series of 512 patients.
Panagis Drakatos,Lucy Marples,Rexford Muza,Sean Higgins,Nadia Gildeh,Raluca Macavei,Eptehal M. Dongol,Alexander Nesbitt,Ivana Rosenzweig,Elaine Lyons,Grainne D'Ancona,Joerg Steier,Adrian J. Williams,Brian D. Kent,Guy D. Leschziner,Guy D. Leschziner +15 more
TL;DR: The treatment approach to effective treatment of the patients with Non-REM parasomnias or POD offering first sleep hygiene advice, next treatment of concurrent sleep disorders and management of other priming factors like stress and anxiety, and lastly pharmacotherapy for Non- REM parasomnia is supported by the results.
Journal ArticleDOI
Benralizumab after sub‐optimal response to mepolizumab in severe eosinophilic asthma
Joanne Kavanagh,Joanne Kavanagh,Andrew P. Hearn,Andrew P. Hearn,Grainne D'Ancona,Jaideep Dhariwal,Cris Roxas,L. Green,L Thomson,Mariana Fernandes,Brian D. Kent,AM Nanzer,David A. Jackson,David A. Jackson +13 more
TL;DR: 10. Kang JY, Kim JW, Kim JS, et al.