G
Greg B. G. Moorhead
Researcher at University of Calgary
Publications - 90
Citations - 4991
Greg B. G. Moorhead is an academic researcher from University of Calgary. The author has contributed to research in topics: Phosphatase & Protein phosphatase 2. The author has an hindex of 33, co-authored 86 publications receiving 4598 citations.
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Journal ArticleDOI
Emerging roles of nuclear protein phosphatases
TL;DR: Recent findings that define the role of nuclear protein phosphatases in controlling transforming growth factor-β and bone-morphogenetic protein (BMP) signalling, the DNA-damage response, RNA processing, cell-cycle progression and gene transcription are discussed.
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14-3-3 proteins: a number of functions for a numbered protein.
Dave Bridges,Greg B. G. Moorhead +1 more
TL;DR: This STKE Review with 2 figures, 1 interactive molecular structure, and 118 references describes 14-3-3 proteins and highlights how these simple proteins have profound effects on the regulation of a vast number of cellular events.
Journal ArticleDOI
Repo-Man recruits PP1γ to chromatin and is essential for cell viability
Laura Trinkle-Mulcahy,Jens B Andersen,Yun Wah Lam,Greg B. G. Moorhead,Matthias Mann,Angus I. Lamond +5 more
TL;DR: The data indicate that Repo-Man forms an essential complex with PP1γ and is required for the recruitment of PP1 to chromatin, and this dominant-negative mutant causes large-scale cell death by apoptosis.
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Phosphate Starvation Inducible ;Bypasses' of Adenylate and Phosphate Dependent Glycolytic Enzymes in Brassica nigra Suspension Cells.
TL;DR: It is hypothesized that pyrophosphate:fructose 6-ph phosphate 1-phosphotransferase, nonphosphorylating NADP-glyceraldehyde 3- phosphate dehydrogenase, and phosphoenolpyruvate phosphatase bypass nucleotide phosphate or Pi-dependent glycolytic reactions during sustained periods of Pi depletion.
Journal ArticleDOI
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A
Aaron A. Goodarzi,Jyoti C Jonnalagadda,Pauline Douglas,David B. Young,Ruiqiong Ye,Greg B. G. Moorhead,Susan P. Lees-Miller,Kum Kum Khanna +7 more
TL;DR: It is proposed that PP2A plays an important role in the regulation of ATM autophosphorylation and activity in vivo, and it is shown that IR induces phosphorylation‐dependent dissociation ofPP2A from ATM and loss of the associated protein phosphatase activity.