G
Greg Fegan
Researcher at Swansea University
Publications - 112
Citations - 4577
Greg Fegan is an academic researcher from Swansea University. The author has contributed to research in topics: Population & Malaria. The author has an hindex of 35, co-authored 103 publications receiving 4150 citations. Previous affiliations of Greg Fegan include Kenya Medical Research Institute & Tulane University.
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Journal ArticleDOI
Mesalazine in the initial management of severely acutely malnourished children with environmental enteric dysfunction: a pilot randomized controlled trial
Kelsey D. J. Jones,Kelsey D. J. Jones,Barbara Hünten-Kirsch,Ahmed Laving,Caroline W Munyi,Moses Ngari,Jenifer Mikusa,Musa Mulongo,Dennis Odera,H. Samira Nassir,Molline Timbwa,Moses Owino,Greg Fegan,Greg Fegan,Simon Murch,Peter B. Sullivan,John O. Warner,James A. Berkley,James A. Berkley +18 more
TL;DR: Intestinal inflammation in EED is non-essential for mucosal homeostasis and is at least partly maladaptive; further trials of gut-specific immunomodulatory therapies targeting host inflammatory activation in order to optimize the growth benefits of nutritional rehabilitation and to address stunting are warranted.
Journal ArticleDOI
Mortality after Inpatient Treatment for Severe Pneumonia in Children: a Cohort Study.
Moses Ngari,Greg Fegan,Greg Fegan,Martha Mwangome,Mwanajuma Ngama,Neema Mturi,John Anthony Scott,John Anthony Scott,Evasius Bauni,David James Nokes,David James Nokes,James A. Berkley,James A. Berkley +12 more
TL;DR: Malnutrition, HIV status, age and prolonged hospitalisation, but not signs of pneumonia severity, were associated with post‐discharge mortality, and risk stratification is needed to reduce mortality after treatment for pneumonia.
Journal ArticleDOI
Targeted screening of at-risk adults for acute HIV-1 infection in sub-Saharan Africa
Eduard J. Sanders,Eduard J. Sanders,Eduard J. Sanders,Elizabeth Wahome,Kimberly A. Powers,Lisa Werner,Greg Fegan,Greg Fegan,Ludo Lavreys,Clement Mapanje,R. Scott McClelland,Nigel Garrett,William C. Miller,Susan M. Graham,Susan M. Graham +14 more
TL;DR: A targeted risk score algorithm based on seven characteristics reduced the number of patients needing AHI testing and had good performance overall, and is recommended for use by HIV programs in sub-Saharan Africa with capacity to test high-risk patients for AHI.
Journal ArticleDOI
Lymphoedema management to prevent acute dermatolymphangioadenitis in podoconiosis in northern Ethiopia (GoLBeT): a pragmatic randomised controlled trial
Henok Negussie,Meseret Molla,Moses Ngari,James A. Berkley,James A. Berkley,Esther Kivaya,Patricia Njuguna,Greg Fegan,Greg Fegan,Abreham Tamiru,Abebe Kelemework,Trudie Lang,Trudie Lang,Melanie J. Newport,Andrew McKay,Fikre Enquoselassie,Gail Davey,Gail Davey +17 more
TL;DR: A simple, inexpensive package of lymphoedema self-care is effective in reducing the frequency and duration of acute dermatolymphangioadenitis in adult patients with podoconiosis in northern Ethiopia.
Journal ArticleDOI
Impaired everyday memory associated with encephalopathy of severe malaria: The role of seizures and hippocampal damage
Michael Kihara,Julie A. Carter,Penny Holding,Faraneh Vargha-Khadem,Rod C. Scott,Richard Idro,Richard Idro,Greg Fegan,Greg Fegan,Michelle de Haan,Brian G. R. Neville,Charles R. Newton,Charles R. Newton,Charles R. Newton +13 more
TL;DR: Exposure to cerebral malaria was associated with a specific impairment of everyday memory and seizures commonly observed in severe malaria may not have a causal relationship with poor outcome, but rather be associated with profound coma and repeated metabolic insults (multi-hypoglycaemia) that are strongly associated with impaired everyday memory.