G
Gregory A. Bohach
Researcher at University of Idaho
Publications - 79
Citations - 4428
Gregory A. Bohach is an academic researcher from University of Idaho. The author has contributed to research in topics: Superantigen & Staphylococcus aureus. The author has an hindex of 36, co-authored 79 publications receiving 4245 citations. Previous affiliations of Gregory A. Bohach include Mississippi State University.
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Journal ArticleDOI
Use of Multiplex PCR To Detect Classical and Newly Described Pyrogenic Toxin Genes in Staphylococcal Isolates
TL;DR: It is shown here, using S. aureus isolates with characterized PT phenotypes, that this novel PCR technique reliably detects each of the known PTs in a single reaction.
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Standard Nomenclature for the Superantigens Expressed by Staphylococcus
Gerard Lina,Gregory A. Bohach,Sean P. Nair,Keiichi Hiramatsu,Evelyne Jouvin-Marche,Roy A. Mariuzza +5 more
TL;DR: The International Nomenclature Committee for Staphylococcal Superantigens proposes an international procedure for the designation of newly described superantigen and putative superantIGens, a procedure that will be compatible with the new age of genomics.
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Characterization of a Putative Pathogenicity Island from Bovine Staphylococcus aureus Encoding Multiple Superantigens
J. Ross Fitzgerald,Steven R. Monday,Timothy J. Foster,Gregory A. Bohach,P.J. Hartigan,William J. Meaney,Cyril J. Smyth +6 more
TL;DR: In vitro bovine Vbeta-specific lymphocyte expansion analysis by culture supernatants of wild-type strains and of tst and sec-bovine allele replacement mutants revealed that TSST stimulates BTB13-specific T cells whereas SEC-bovoine stimulates BT B93- specific T cells, suggesting that the presence of SaPIbov may contribute to modulation of the bovines immune response.
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A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia
Gillian J. Wilson,Keun Seok Seo,Robyn A. Cartwright,Timothy Connelley,Olivia N. Chuang-Smith,Joseph A. Merriman,Caitriona M. Guinane,Joo Youn Park,Gregory A. Bohach,Patrick M. Schlievert,W. Ivan Morrison,J. Ross Fitzgerald +11 more
TL;DR: A novel SAg staphylococcal enterotoxin-like toxin X (SElX) encoded in the core genome of 95% of phylogenetically diverse S. aureus strains is found, providing new insights into the evolution of pathogenic S.Aureus and the molecular basis for severe infections caused by the CA-MRSA USA300 epidemic clone.
Journal ArticleDOI
Beta toxin catalyzes formation of nucleoprotein matrix in staphylococcal biofilms
M. Huseby,Andrew C. Kruse,Jeff Digre,Petra L. Kohler,Jillian A. Vocke,Ethan E. Mann,Kenneth W. Bayles,Gregory A. Bohach,Patrick M. Schlievert,Douglas H. Ohlendorf,Cathleen A. Earhart +10 more
TL;DR: It is suggested that beta toxin cross-linking in the presence of eDNA assists in forming the skeletal framework upon which staphylococcal biofilms are established.