G
Guglielmo Foffani
Researcher at CEU San Pablo University
Publications - 132
Citations - 5772
Guglielmo Foffani is an academic researcher from CEU San Pablo University. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 36, co-authored 118 publications receiving 4808 citations. Previous affiliations of Guglielmo Foffani include University of Milan & Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.
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Journal ArticleDOI
Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson's disease.
Guglielmo Foffani,Guglielmo Foffani,A. Pesenti,Filippo Tamma,Anna M. Bianchi,M. Pellegrini,Marco Locatelli,Karen A. Moxon,Roberto Villani +8 more
TL;DR: There are at least two rhythms below 50 Hz that are separately modulated by antiparkinsonian medication: one at low frequencies and one in the beta range, consistent with the hypothesis of multiple oscillating systems.
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Adaptive deep brain stimulation (aDBS) controlled by local field potential oscillations.
TL;DR: Current evidence on the advantages of neurosignal-controlled aDBS that uses local field potentials (LFPs) as a control variable is reviewed, and the technology already available to create new DBS systems are described and described.
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Reduced spike-timing reliability correlates with the emergence of fast ripples in the rat epileptic hippocampus
TL;DR: It is proposed that fast ripples emerge from a disorganized ripple pattern caused by unreliable firing in the epileptic hippocampus, and that reducing synaptically driven membrane potential fluctuations improves both spike-timing reliability and spatial synchronization and restores ripples in the epilepsyptic hippocampus.
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300-Hz subthalamic oscillations in Parkinson's disease
Guglielmo Foffani,M. Egidi,Paolo Rampini,Filippo Tamma,E Caputo,Karen A. Moxon,S. Cerutti,Sergio Barbieri +7 more
TL;DR: While recording local field potentials from the STN of nine patients with Parkinson's disease through DBS electrodes, a dopamine- and movement-dependent 300-Hz rhythm was found, which probably reflects a bistable compound nuclear activity and supports high-resolution information processing in the basal ganglia circuit.
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Movement-related frequency modulation of beta oscillatory activity in the human subthalamic nucleus
TL;DR: It is shown that frequency modulation of low‐beta and high‐beta rhythms significantly contributes to the involvement of the human STN in movement preparation, execution and recovery, and that the FM patterns are regulated by the dopamine levels in the system.