G
Guillermo Gosset
Researcher at National Autonomous University of Mexico
Publications - 132
Citations - 6214
Guillermo Gosset is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Escherichia coli & PEP group translocation. The author has an hindex of 45, co-authored 126 publications receiving 5632 citations. Previous affiliations of Guillermo Gosset include University of California, San Diego & Novartis.
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Improvement of Escherichia coli production strains by modification of the phosphoenolpyruvate:sugar phosphotransferase system
TL;DR: Functional replacement of PTS by alternative phosphoenolpyruvate-independent uptake and phosphorylation activities has resulted in significant improvements in product yield from glucose and productivity for several classes of metabolites.
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Transcriptome Analysis of Crp-Dependent Catabolite Control of Gene Expression in Escherichia coli
Guillermo Gosset,Guillermo Gosset,Zhongge Zhang,Samir Nayyar,William A. Cuevas,Milton H. Saier +5 more
TL;DR: The transcriptome analyses of highly expressed genes that are subject to catabolite repression or activation mediated by the cyclic AMP receptor protein (Crp) reveal that many operons encoding enzymes of central carbon metabolic pathways, as well as transporters and enzymes that initiate carbon metabolism, aresubject to direct Crp-mediated catabolites repression.
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Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system
Karla Xadany Cabral Martínez,Ramón de Anda,Georgina Hernández,Adelfo Escalante,Guillermo Gosset,Octavio T. Ramírez,Francisco Bolívar +6 more
TL;DR: Due to the lack of catabolite repression, PB12 strain carrying multicopy plasmids containing tktA and aroGfbrgenes is capable of coutilizing glucose and other carbon sources; this capacity, reduces its μ but increases the production of aromatic compounds.
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Expression of galP and glk in a Escherichia coli PTS mutant restores glucose transport and increases glycolytic flux to fermentation products
Verónica Hernández-Montalvo,Alfredo Martinez,Georgina Hernández-Chávez,Francisco Bolívar,Fernando Valle,Guillermo Gosset +5 more
TL;DR: The purpose of this work was to study the effect of different gene expression levels, of galactose permease (GalP) and glucokinase (Glk), on glucose internalization and phosphorylation in a E. coli PTS− strain.
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Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds
Alberto Rodriguez,Juan A Martnez,Noem Flores,Adelfo Escalante,Guillermo Gosset,Francisco Bolívar +5 more
TL;DR: This paper reviews and compares recent successful reports dealing with the modification of metabolic traits to attain the goals of generation, characterization and optimization of E. coli strains for the overproduction of aromatic amino acids, some of their precursors and related compounds.