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Guislaine Refrégier

Researcher at Université Paris-Saclay

Publications -  59
Citations -  1817

Guislaine Refrégier is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Mycobacterium tuberculosis & Mycobacterium tuberculosis complex. The author has an hindex of 20, co-authored 49 publications receiving 1645 citations. Previous affiliations of Guislaine Refrégier include Centre national de la recherche scientifique & University of Paris-Sud.

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Cospeciation vs host-shift speciation: methods for testing, evidence from natural associations and relation to coevolution

TL;DR: Overall, there is now substantial evidence to suggest that coevolutionary dynamics of hosts and parasites do not favor long-term cospeciation, and approaches to compare divergence between pairwise associated groups of species, their advantages and pitfalls are outlined.
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Speciation in fungi

TL;DR: This review on fungal speciation first contrast the issues of species definition and species criteria and show that by distinguishing the two concepts the approaches to studying the speciation can be clarified.
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Cophylogeny of the anther smut fungi and their caryophyllaceous hosts: prevalence of host shifts and importance of delimiting parasite species for inferring cospeciation.

TL;DR: Genetic similarity underlying the host-parasite interactions appeared to have the most important influence on specialization and host-shifts: generalist multi-host parasite species were found on closely related plant species, and related species in the Microbotryum phylogeny were associated with members of the same host clade.
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Mating system of the anther smut fungus Microbotryum violaceum: selfing under heterothallism.

TL;DR: The origin of sex chromosomes is believed to have involved suppression of recombination around the essential sex determining genes on an ancestral autosomal pair and progressive expansion of this region of suppressed recombination through the recruitment of other sex-related factors.
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Mycobacterium tuberculosis complex CRISPR genotyping: improving efficiency, throughput and discriminative power of 'spoligotyping' with new spacers and a microbead-based hybridization assay.

TL;DR: A limited yet highly informative reduced 10 spacer panel set is defined which could offer a more cost-effective option for implementation in resource-limited countries and that could decrease the need for additional VNTR genotyping work in molecular epidemiological studies.