Antoine Andremont

TL;DR: It is suggested that CTX-M carriage is evolving toward a global pandemic but is still insufficiently described, and only a better knowledge of its dynamics and biology will lead to further development of appropriate control measures.

TL;DR: In this paper, the authors performed a prospective, international, observational study of 844 hospitalized patients with blood cultures positive for Streptococcus pneumoniae and evaluated the impact of concordant antibiotic therapy (i.e., receipt of a single antibiotic with in vitro activity against S. pneumoniae) versus discordant therapy (inactive in vitro) on mortality at 14 days.

TL;DR: Combination antibiotic therapy improved survival among critically ill patients with bacteremic pneumococcal illness, independent of country of origin, intensive care unit support, class of antibiotics, or in vitro activity of the antibiotics prescribed.

TL;DR: It is shown that overcolonization of farmers was caused by a few bacterial strains that were not present in nonfarmers but often caused swine infections, which suggests a high rate of strain exchange between pigs and farmers.

TL;DR: It seems clear that such drug carriers (liposomes, nanoparticles) allow increased drug concentration at infected sites but reduce drug toxicity.