X
Xu Wu
Researcher at Chinese Ministry of Education
Publications - 20
Citations - 2710
Xu Wu is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Nasopharyngeal carcinoma & Tumor microenvironment. The author has an hindex of 11, co-authored 20 publications receiving 1410 citations. Previous affiliations of Xu Wu include Nanchang University & Central South University.
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Journal ArticleDOI
Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape.
Xianjie Jiang,Xianjie Jiang,Jie Wang,Xiangying Deng,Fang Xiong,Junshang Ge,Junshang Ge,Bo Xiang,Bo Xiang,Xu Wu,Xu Wu,Jian Ma,Jian Ma,Ming Zhou,Ming Zhou,Xiaoling Li,Xiaoling Li,Yong Li,Yong Li,Guiyuan Li,Guiyuan Li,Wei Xiong,Wei Xiong,Can Guo,Can Guo,Zhaoyang Zeng,Zhaoyang Zeng +26 more
TL;DR: Overall, the evidence accumulated to date suggests that induction of PD-L1 by inflammatory factors in the tumor microenvironment may be one of the most important factors affecting the therapeutic efficiency of PD -L1/PD-1 blocking.
Journal ArticleDOI
Circular RNAs function as ceRNAs to regulate and control human cancer progression.
Yaxian Zhong,Yaxian Zhong,Yajun Du,Yajun Du,Xue Yang,Xue Yang,Yongzhen Mo,Yongzhen Mo,Chunmei Fan,Fang Xiong,Daixi Ren,Daixi Ren,Xin Ye,Xin Ye,Chunwei Li,Chunwei Li,Yumin Wang,Yumin Wang,Fang Wei,Can Guo,Xu Wu,Xiaoling Li,Xiaoling Li,Yong Li,Yong Li,Guiyuan Li,Guiyuan Li,Zhaoyang Zeng,Zhaoyang Zeng,Wei Xiong,Wei Xiong +30 more
TL;DR: The progress in studying the role of circRNAs as ceRNAs in tumors is reviewed and the participation of circ RNAs in signal transduction pathways to regulate cellular functions is highlighted.
Journal ArticleDOI
Neoantigen vaccine: an emerging tumor immunotherapy
Miao Peng,Miao Peng,Yongzhen Mo,Yian Wang,Pan Wu,Yijie Zhang,Fang Xiong,Can Guo,Xu Wu,Xu Wu,Yong Li,Xiaoling Li,Guiyuan Li,Guiyuan Li,Wei Xiong,Wei Xiong,Zhaoyang Zeng,Zhaoyang Zeng +17 more
TL;DR: Tumor vaccines targeting neoantigens mainly include nucleic acid, dendritic cell (DC)-based, tumor cell, and synthetic long peptide (SLP) vaccines, which might achieve better therapeutic effects in the future.
Journal ArticleDOI
Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA
Pan Wu,Pan Wu,Yongzhen Mo,Miao Peng,Ting Tang,Yu Zhong,Xiangying Deng,Fang Xiong,Can Guo,Xu Wu,Xu Wu,Yong Li,Xiaoling Li,Guiyuan Li,Guiyuan Li,Zhaoyang Zeng,Zhaoyang Zeng,Wei Xiong,Wei Xiong +18 more
TL;DR: The aim of this review is to provide a theoretical basis and relevant references, which may promote the discovery of more functional peptides encoded by ncRNAs, and further develop novel anticancer therapeutic targets, as well as diagnostic and prognostic cancer markers.
Journal ArticleDOI
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway
Yu Lian,Yu Lian,Yu Lian,Fang Xiong,Fang Xiong,Liting Yang,Liting Yang,Hao Bo,Zhaojian Gong,Yumin Wang,Fang Wei,Fang Wei,Yanyan Tang,Yanyan Tang,Xiayu Li,Qianjin Liao,Qianjin Liao,Hui Wang,Ming Zhou,Ming Zhou,Bo Xiang,Bo Xiang,Xu Wu,Xu Wu,Li Yong,Li Yong,Xiaoling Li,Xiaoling Li,Xiang Chen,Guiyuan Li,Guiyuan Li,Can Guo,Can Guo,Zhaoyang Zeng,Zhaoyang Zeng,Wei Xiong,Wei Xiong +36 more
TL;DR: In this article, the role of actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1), a long noncoding RNA, is investigated in vitro and in vivo.