G
Gunter Weiss
Researcher at Max Planck Society
Publications - 17
Citations - 3135
Gunter Weiss is an academic researcher from Max Planck Society. The author has contributed to research in topics: Population & Regulation of gene expression. The author has an hindex of 16, co-authored 17 publications receiving 3048 citations. Previous affiliations of Gunter Weiss include University of Düsseldorf.
Papers
More filters
Journal ArticleDOI
Parallel Patterns of Evolution in the Genomes and Transcriptomes of Humans and Chimpanzees
Philipp Khaitovich,Ines Hellmann,Wolfgang Enard,Katja Nowick,Marcus Leinweber,Marcus Leinweber,Henriette Franz,Gunter Weiss,Michael Lachmann,Svante Pääbo +9 more
TL;DR: It is found that genes active in brain have accumulated more changes on the human than on the chimpanzee lineage, and patterns suggestive of positive selection on sequence changes as well as expression changes are seen.
Journal ArticleDOI
A neutral model of transcriptome evolution.
Philipp Khaitovich,Gunter Weiss,Michael Lachmann,Ines Hellmann,Wolfgang Enard,Bjoern Muetzel,Ute Wirkner,Wilhelm Ansorge,Svante Pääbo +8 more
TL;DR: The results suggest that the majority of expression differences observed between species are selectively neutral or nearly neutral and likely to be of little or no functional significance, which should be based on null hypotheses assuming functional neutrality.
Journal ArticleDOI
Regional patterns of gene expression in human and chimpanzee brains.
Philipp Khaitovich,Bjoern Muetzel,Xinwei She,Michael Lachmann,Ines Hellmann,Janko Dietzsch,Stephan Steigele,Hong Hai Do,Gunter Weiss,Wolfgang Enard,Florian Heissig,Thomas Arendt,Kay Nieselt-Struwe,Evan E. Eichler,Svante Pääbo +14 more
TL;DR: A subset of genes that show expression differences between humans and chimpanzees are distributed nonrandomly across the genome and are statistically significantly enriched in regions that are recently duplicated in humans.
Journal ArticleDOI
Pattern of Nucleotide Substitution and Rate Heterogeneity in the Hypervariable Regions I and II of Human mtDNA
TL;DR: The results indicate that the rate of substitution in HVRI is approximately twice as high as in HVRII and that this difference is mainly due to a higher frequency of pyrimidine transitions in HvRI, while rate heterogeneity is more pronounced in HvrII.
Journal ArticleDOI
Great ape DNA sequences reveal a reduced diversity and an expansion in humans.
TL;DR: It is shown that humans differ from the great apes in having a low level of genetic variation and a signal of population expansion.