Guodong Li

TL;DR: A novel iridium(III)-based probe 1 is designed and synthesized for discriminating ovarian carcinoma cell lines from normal cell lines and could be potentially used as a useful probe for detecting β-gal expression in the context of ovarian cancer diagnostics.

TL;DR: This study reports the first use of an iridium(iii) compound and its enantiomer to inhibit the H-Ras/Raf-I PPI in vitro and repress renal cancer xenografts in vivo.

TL;DR: A long-lived complex 13 could selectively bind to dopamine receptors (D1R/D2R) and monitor their internalization in living cells.

TL;DR: Optical imaging possesses a number of notable advantages that renders it as an attractive diagnostic modality, and transition metal complexes have attracted recent attention as alternatives to conventional dyes due to their advantages of large Stokes shifts, long lifetimes, and ease of structural modifications.

TL;DR: A novel rhodium(III) complex 1 was selective for LSD1 over other histone demethylases, such as KDM2b, KDM7, and MAO activities, and also showed antiproliferative activity toward human cancer cells and is the first metal-based inhibitor of LSD1 activity.