D
Dik-Lung Ma
Researcher at Hong Kong Baptist University
Publications - 340
Citations - 15331
Dik-Lung Ma is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Virtual screening & Chemistry. The author has an hindex of 65, co-authored 321 publications receiving 12947 citations. Previous affiliations of Dik-Lung Ma include Baptist College of Health Sciences & Yale University.
Papers
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New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics.
Si Yuan Pan,Shu-Feng Zhou,Si Hua Gao,Zhi-Ling Yu,Shuo Feng Zhang,Min Ke Tang,Jian Ning Sun,Dik-Lung Ma,Yifan Han,Wang Fun Fong,Kam Ming Ko +10 more
TL;DR: The prospect of drug discovery from herbal medicines in the postgenomic era was made with the provision of future directions in this area of drug development.
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Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives
Tian-Miao Ou,Yu-Jing Lu,Chi Zhang,Zhi-Shu Huang,Xiao-Dong Wang,Jia-Heng Tan,Yuan Chen,Dik-Lung Ma,Kwok Yin Wong,Johnny Cheuk On Tang,Albert S. C. Chan,Lian-Quan Gu +11 more
TL;DR: Molecular modeling studies revealed the binding mode between the derivatives and the G-quadruplexes is end-stacking at the 3'-position, and the positively charged side chain on the quindoline derivatives may contribute to the selectivity to certain loop isomers of topological quadruplexes as the improved stabilization action.
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Recent advances in luminescent heavy metal complexes for sensing
Dik-Lung Ma,Victor Pui-Yan Ma,Daniel Shiu-Hin Chan,Ka-Ho Leung,Hong-Zhang He,Chung-Hang Leung +5 more
TL;DR: Luminescent metal complexes have attracted increasing attention in the literature over the last few decades as discussed by the authors, and transition metal compounds have been widely studied for luminescent sensing applications due to their attractive photophysical properties.
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Bioactive iridium and rhodium complexes as therapeutic agents
TL;DR: A review of the recent strategies that have been utilized for the design and development of bioactive iridium and rhodium complexes can be found in this article, where the authors summarize the strategies used for the development and design of bio-active IR and RRS complexes.
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Platinum(II) complexes with dipyridophenazine ligands as human telomerase inhibitors and luminescent probes for G-quadruplex DNA.
TL;DR: Using a biotinylated-primer extension telomerase assay, 1 was shown to be an effective inhibitor of human telomersase in vitro, with a telIC50 value of 760 nM.